Evidence map›Paper›PMID 16041049›Full record

ArticleInfection and immunity2005

Recombinant proteins of Cryptosporidium parvum induce proliferation of mesenteric lymph node cells in infected mice.

Inderpal Singh, Cynthia Theodos, Saul Tzipori

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Frontiers in veterinary science · 2026
    Review
  2. Article
  3. mFrontiers in immunology · 2021
    Article
  4. Systemic and Mucosal Immune Responses toCurrent tropical medicine reports · 2015
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Inderpal SinghDivision of Infectious Diseases, Department of Biomedical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA. inderpal.singh@tufts.edu
Cynthia Theodos
Saul Tzipori
Tufts University · USBiogen (United States) · US

Funding

Wasting, nutritional status, and micronutrientsP01DK055510 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MANSFIELD, KEITH G. · 2000 to 2004
$5.8M
INTERFERON GAMMA AND THE IMMUNE RESPONSE TO C PARVUMR29AI039967 · NIAID · TUFTS UNIVERSITY BOSTON · PI THEODOS, CYNTHIA M · 1996 to 2000
$125k
NIAID NIH HHS R29-AI39967NIDDK NIH HHS P01 DK055510NIDDK NIH HHS P01-DK55510
6 · The paper itself

Abstract

Recombinant antigens of Cryptosporidium parvum, Cp900 and Cp40 but not Cp15, stimulated C. parvum-specific proliferative immune responses of mesenteric lymph node cells in C57BL/6J mice infected with different isolates (MD, GCH1, UCP, and IOWA) of C. parvum, indicating that both Cp900 and Cp40 are immunodominant targets of cellular immune responses during C. parvum infection.

Indexed as

Cell ProliferationAnimalsCryptosporidium parvumLymph NodesMiceMice, Inbred C57BLProtozoan ProteinsRecombinant ProteinsCP15 protein, Cryptosporidium parvumProtozoan ProteinsRecombinant Proteins

Identifiers

PMID16041049
PMCPMC1201208
OpenAlexW2154812117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.