Evidence map›Paper›PMID 16041041›Full record

ArticleInfection and immunity2005

Identification of variant-specific surface proteins in Giardia muris trophozoites.

Andrea S Ropolo, Alicia Saura, Pedro G Carranza, Hugo D Lujan

Abstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The compact genome ofMicrobial genomics · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea S RopoloCátedra de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Nacional de Córdoba, Haya de la Torre S/N, Pabellón Argentina 2do piso, Ciudad Universitaria, CP 5000 Córdoba, Argentina.
Alicia Saura
Pedro G Carranza
Hugo D Lujan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giardia lamblia undergoes antigenic variation, a process that might allow the parasite to evade the host's immune response and adapt to different environments. Here we show that Giardia muris, a related species that naturally infects rodents, possesses multiple variant-specific surface proteins (VSPs) and expresses VSPs on its surface, suggesting that it undergoes antigenic variation similar to that of G. lamblia.

Indexed as

Amino Acid SequenceAnimalsBlotting, NorthernGiardiaGiardiasisMembrane ProteinsMolecular Sequence DataRatsRats, WistarMembrane Proteins

Identifiers

PMID16041041
PMCPMC1201240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.