ReviewWorld journal of gastroenterology2005
Treatment of uncomplicated reflux disease.
Review in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.Journal of pediatric gastroenterology and nutrition · 2018Guideline
- LINXSurgical endoscopy · 2017Pooled it
- New treatment method for refractory gastroesophageal reflux disease (GERD): C-BLART (clip band ligation anti-reflux therapy)-a short-term study.Surgical endoscopy · 2020Trial
- Randomized, multicenter study: on-demand versus continuous maintenance treatment with esomeprazole in patients with non-erosive gastroesophageal reflux disease.BMC gastroenterology · 2016Trial
- Efficacy and safety of omeprazole in Japanese patients with nonerosive reflux disease.Journal of gastroenterology · 2008Trial
- Pepsin in saliva for the diagnosis of erosive esophagitis post-sleeve gastrectomy: a prospective observational study.Surgical endoscopy · 2023Observational
- Complete endoscopic removal of an eroded magnetic sphincter augmentation device.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2021Article
- Non-surgical animal model of gastroesophageal reflux disease by overeating induced in mice.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021Article
- Acid Suppression Use Among Infants in One Tertiary Children's Hospital in China, 2015-2018: A Retrospective Observational Study.Frontiers in pediatrics · 2021Article
- Antireflux mucosectomy band in treatment of refractory gastroesophageal reflux disease: a pilot study for safety, feasibility and symptom control.Endoscopy international open · 2020Article
- Article
- Gastro-oesophageal reflux disease and eosinophilic oesophagitis: What is the relationship?World journal of gastrointestinal pathophysiology · 2018Review
- The Role of Proton Pump Inhibitors in the Management of Upper Gastrointestinal Disorders.Gastroenterology & hepatology · 2018Article
- Medical Treatment of Gastroesophageal Reflux Disease.World journal of surgery · 2017Review
- Severe adverse reactions caused by omeprazole: A case report.Experimental and therapeutic medicine · 2016Article
- Presence of minimal change esophagitis closely correlates with pathological conditions in the stomach.Digestive diseases and sciences · 2012Article
- The pain system in oesophageal disorders: mechanisms, clinical characteristics, and treatment.Gastroenterology research and practice · 2011Article
- Functional heartburn, nonerosive reflux disease, and reflux esophagitis are all distinct conditions--a debate: con.Current treatment options in gastroenterology · 2007Article
- Polymorphisms of glutathione S-transferase M1, T1 and P1 in patients with reflux esophagitis and Barrett's esophagus.Journal of human genetics · 2007Article
- Formulary Substitution of Proton Pump Inhibitors Based on Acquisition Price: Changes in Usage and Costs of Acid-Suppressant Therapies.P & T : a peer-reviewed journal for formulary management · 2006Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uncomplicated reflux disease comprises the non-erosive reflux disease (NERD) and erosive reflux disease (ERD). The objectives of treatment are the adequate control of symptoms with restoration of quality of life, healing of lesions and prevention of relapse. Treatment of NERD consists in the administration of proton pump inhibitors (PPI) for 2-4 wk, although patients with NERD show an overall poorer response to PPI treatment than patients with ERD owing to the fact that patients with NERD do not form a pathophysiologically homogenous group. For long-term management on-demand treatment with a PPI is probably the best option. In patients with ERD, therapy with a standard dose PPI for 4-8 wk is always recommended. Long-term treatment of ERD is applied either intermittently or as continuous maintenance treatment with an attempt to reduce the daily dosage of the PPI (step-down principle). In selected patients requiring long-term PPI treatment, antireflux surgery is an alternative option. In patients with troublesome reflux symptoms and without alarming features empirical PPI therapy is another option for initial management. Therapy should be withdrawn after initial success. In the case of relapse, the long-term care depends on a careful risk assessment and the response to PPI therapy.
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