SynthesisThe Cochrane database of systematic reviews2005
Inhaled beta2-agonists for treating non-specific chronic cough in children.
Synthesis in The Cochrane database of systematic reviews, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- [Consensus statement on the evaluation and therapy of chronic cough in children].Wiener klinische Wochenschrift · 2014Guideline
- Inhaled beta2-agonists for treating non-specific chronic cough in children.The Cochrane database of systematic reviews · 2005Pooled it
- Latino-white disparities in ICD-coded asthma diagnosis among US children.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022Article
- Effects of Oral Procaterol for Postinfectious Cough in Adults: Single-Centre, Randomized Double-Blind, Placebo-Controlled Trial.Korean journal of family medicine · 2021Article
- Analysis of the Literature on Chronic Cough in Children.The open respiratory medicine journal · 2017Review
- Prolonged Cough in Pediatric Population First Line Care, Belgian Guidelines.The open respiratory medicine journal · 2017Article
- Suppressive effects of procaterol on expression of IP-10/CXCL 10 and RANTES/CCL 5 by bronchial epithelial cells.Inflammation · 2011Article
- Asthma.BMJ (Clinical research ed.) · 2007Review
- A paper that changed my practice: S McKenzie. Cough but is it asthma? Arch Dis Child 1994;70:1-2.Archives of disease in childhood · 2007Review
- Whooping cough in general practice.BMJ (Clinical research ed.) · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pathophysiology of so called 'cough variant asthma' has not received a great deal of research interest and opinion lies divided as to whether it is really asthma or not. The proponents of cough variant asthma suggest a therapeutic trial of medications usually used to treat asthma
objectivesTo determine the effectiveness of inhaled ss2 agonists in non-specific chronic cough in children over the age of 2 years. SEARCH STRATEGY: The Cochrane Airways Group database (including MEDLINE, EMBASE and CINAHL) and the Cochrane Controlled Trials Register (CCRT) were searched. Additional searching included hand searching of medical journals through the Cochrane Collaboration, references, references of references listed in primary sources and personal communication with authors. In addition "Grey literature" including theses, internal reports, non-peer reviewed journals were sought. SELECTION CRITERIA: All randomised (randomised and quasi-randomised) controlled clinical trials in which inhaled ss2 agonists were given for chronic cough in children over 2 years of age were included. Two reviewers independently assessed articles for inclusion and methodological quality. DATA COLLECTION AND ANALYSIS: Data for trials of salbutamol versus placebo were extracted by both reviewers and entered into the Cochrane Collaboration software program Review Manager, version 4.2 MAIN
resultsIn children presenting with isolated chronic cough there was no significant difference between salbutamol treated group and placebo group. AUTHORS'
conclusionsSalbutamol was no different from placebo in reducing the frequency of cough measured objectively or scored subjectively.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.