Evidence map›Paper›PMID 16034556›Full record

Trial reportPsychopharmacology2005

Influence of the duration of abstinence on the relative reinforcing effects of cigarette smoking.

Jennifer Plebani Lussier, Stephen T Higgins, Gary J Badger

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Psychopharmacology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. A Secondary Analysis of a Preliminary Contingency Management Intervention for Presurgical Cancer Patients: Evaluating Individual Participant Data.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Trial
  4. Trial
  5. Examining Age as a Potential Moderator of Response to Reduced Nicotine Content Cigarettes in Vulnerable Populations.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Trial
  6. A randomized trial of contingency management for smoking cessation in the homeless.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018
    Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Contingency management and motivational enhancement: a randomized clinical trial for college student smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2009
    Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Article
  19. Article
  20. Potential Moderating Effects of Psychiatric Diagnosis and Symptom Severity on Subjective and Behavioral Responses to Reduced Nicotine Content Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jennifer Plebani LussierDepartment of Psychology, University of Vermont, Burlington, VT, USA.
Stephen T Higgins
Gary J Badger
University of Vermont · USUniversity of Vermont Medical Center · US

Funding

TRAINING IN BEHAV. PHARMACOLOGY OF HUMAN DRUG DEPENDENCET32DA007242 · NIDA · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI HEIL, SARAH H, HIGGINS, STEPHEN T · 1990 to 2025
$8.2M
Modeling Initial Smoking Abstinence and Relapse RiskR01DA008076 · NIDA · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 1993 to 2010
$2.8M
NIDA NIH HHS R01DA08076NIDA NIH HHS T32DA07242
6 · The paper itself

Abstract

rationaleSustaining smoking abstinence during the initial weeks of a cessation effort is highly correlated with long-term smoking abstinence. However, experimental research is needed to establish a direct causal relationship between achieving early abstinence and lowered relapse risk.

objectiveIn the present study, we tested whether a period of sustained abstinence directly decreases the relative reinforcing effects of cigarette smoking.

methodsParticipants were 63 adult smokers who were randomized into one of three conditions: 14-day (14C), 7-day (7C), and 1-day (1C) contingent payment for smoking abstinence. Smoking status was assessed three times per day for 14 consecutive days using breath carbon monoxide monitoring and an abstinence criterion of < or = 4 ppm. In the 14C condition, monetary payment was contingent on abstinence for all 14 days; in the 7C condition, payment was noncontingent for days 1-7 and contingent for days 8-14; in the 1C condition, payment was noncontingent for days 1-13 and contingent for day 14. On day 14, all participants completed a 3-h preference session under controlled laboratory conditions wherein they could make a maximum of 20 exclusive choices between options to smoke (two puffs/choice) or earn money (0.25 dollars/choice). Preference was deemed an index of the relative reinforcing effects of smoking and money.

resultsA significantly lower proportion of participants in the 14C condition ever chose the smoking option (19%) compared to those in the 7C (57%) or 1C (62%) conditions.

conclusionsThese results provide experimental evidence that sustained abstinence can decrease the relative reinforcing effects of smoking, an effect that may be related to the commonly observed decrease in relapse risk among those who are able to sustain smoking abstinence during the initial weeks of a cessation effort.

Indexed as

MotivationReinforcement, PsychologyAdultChoice BehaviorFemaleHumansMaleMiddle AgedPain MeasurementRecurrenceSmokingSmoking CessationTime Factors

Identifiers

PMID16034556
OpenAlexW1988689420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.