ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2005
Evidence for an instructive role of retinal activity in retinotopic map refinement in the superior colliculus of the mouse.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.
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Who cites it
106 citing papers in PubMed.
- Retinal waves shape starburst amacrine cell dendrite development through a direction-selective dendritic computation.Cell reports · 2026Article
- Mouse model of Angelman syndrome exhibits reduced retinal activity during development.Frontiers in neuroscience · 2026Article
- Light-evoked activity and BDNF regulate mitochondrial dynamics and mitochondrial localized translation in CNS axons.iScience · 2025Article
- Chilean brush-tailed mouse (Journal of neurophysiology · 2025Article
- Disruption of Cholinergic Retinal Waves Alters Visual Cortex Development and Function.bioRxiv : the preprint server for biology · 2024Article
- Involvement of the superior colliculi in crossmodal correspondences.Attention, perception & psychophysics · 2024Article
- Mapping the Retina onto the Brain.Cold Spring Harbor perspectives in biology · 2024Review
- Unsupervised learning on spontaneous retinal activity leads to efficient neural representation geometry.ArXiv · 2023Article
- Topographic axonal projection at single-cell precision supports local retinotopy in the mouse superior colliculus.Nature communications · 2023Article
- Retinal waves align the concentric orientation map in mouse superior colliculus to the center of vision.Science advances · 2023Article
- Role of glutamate in the development of visual pathways.Frontiers in ophthalmology · 2023Review
- Synaptic properties of mouse tecto-parabigeminal pathways.Frontiers in systems neuroscience · 2023Article
- Developmental spontaneous activity promotes formation of sensory domains, frequency tuning and proper gain in central auditory circuits.Cell reports · 2022Article
- Developmental stage-specific spontaneous activity contributes to callosal axon projections.eLife · 2022Article
- Manipulating the Level of Sensorimotor Stimulation during LI-rTMS Can Improve Visual Circuit Reorganisation in Adult Ephrin-A2A5International journal of molecular sciences · 2022Article
- Epigenetic and Transcriptional Regulation of Spontaneous and Sensory Activity Dependent Programs During Neuronal Circuit Development.Frontiers in neural circuits · 2022Review
- To Stick or Not to Stick: The Multiple Roles of Cell Adhesion Molecules in Neural Circuit Assembly.Frontiers in neuroscience · 2022Review
- Live imaging of retinotectal mapping reveals topographic map dynamics and a previously undescribed role for Contactin 2 in map sharpening.Development (Cambridge, England) · 2021Article
- Building a circuit through correlated spontaneous neuronal activity in the developing vertebrate and invertebrate visual systems.Genes & development · 2021Review
- Short-Term Visual Experience Leads to Potentiation of Spontaneous Activity in Mouse Superior Colliculus.Neuroscience bulletin · 2021Article
46 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
Although it is widely accepted that molecular mechanisms play an important role in the initial establishment of retinotopic maps, it has also long been argued that activity-dependent factors act in concert with molecular mechanisms to refine topographic maps. Evidence of a role for retinal activity in retinotopic map refinement in mammals is limited, and nothing is known about the effect of spontaneous retinal activity on the development of receptive fields in the superior colliculus. Using anatomical and physiological methods with two genetically manipulated mouse models and pharmacological interventions in wild-type mice, we show that spontaneous retinal waves instruct retinotopic map refinement in the superior colliculus of the mouse. Activity-dependent mechanisms may play a preferential role in the mapping of the nasal-temporal axis of the retina onto the colliculus, because refinement is particularly impaired along this axis in mutants without retinal waves. Interfering with both axon guidance cues and activity-dependent cues in the same animal has a dramatic cumulative effect. These experiments demonstrate how axon guidance cues and activity-dependent factors combine to instruct retinotopic map development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.