ReviewDrugs2005
Impact of smoking on asthma therapy: a critical review of clinical evidence.
Review in Drugs, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 44 citations in OpenAlex.
- Effect of smoking status on lung function, patient-reported outcomes, and safety among COPD patients treated with glycopyrrolate inhalation powder: pooled analysis of GEM1 and GEM2 studies.Respiratory research · 2019Trial
- Group 3 Innate Lymphoid Cells: A Potential Therapeutic Target for Steroid Resistant Asthma.Clinical reviews in allergy & immunology · 2024Review
- Association between high school students' cigarette smoking, asthma and related beliefs: a population-based study.BMC public health · 2016Article
- Stratified approaches to the treatment of asthma.British journal of clinical pharmacology · 2013Review
- Impact of smoking on asthma symptoms, healthcare resource use, and quality of life outcomes in adults with persistent asthma.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2007Article
- The prevalence of DSM-IV anxiety and depressive disorders in youth with asthma compared with controls.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2007Article
- Influence of current or former smoking on asthma management and control.Canadian respiratory journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Airway inflammation is central to the pathophysiology of asthma, with treatment directed towards modification of this inflammation and its consequences. The relationship between cigarette smoking and airway inflammation is also well described, but relatively little data are available on the potential influence of smoking on asthmatic airway inflammation and its treatment. While cigarette smoking is common in people with asthma, with prevalence rates similar to the general population, studies in asthma have tended to concentrate on individuals who have never smoked. However, there is recent evidence that smoking may confer a degree of corticosteroid resistance in asthma, and this review examines the relationship between asthma and cigarette smoking, with particular reference to the impact of smoking on the response to treatment of asthma. Smoking has a number of known influences on drug activity and metabolism, but the mechanism underlying corticosteroid resistance in asthmatic smokers is not yet clear, although there are differences in the nature of the airway inflammation in individuals with asthma who smoke compared with nonsmoking asthmatic patients. Encouragingly, there is some evidence that smoking cessation may at least partially restore corticosteroid responsiveness in asthmatic ex-smokers. Smoking cessation measures must be given a high priority in individuals with asthma who smoke.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.