ArticleThe Journal of infectious diseases2005
Frequent detection of polyomaviruses in stool samples from hospitalized children.
Article in The Journal of infectious diseases, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 98 citations in OpenAlex.
- Recent Insights into the Pathogenesis, Diagnostics, and Treatment of BK Virus Infections in Children After Hematopoietic Stem Cell Transplantation.Pathogens (Basel, Switzerland) · 2025Review
- Evaluating Nanotrap Microbiome Particles as A Wastewater Viral Concentration Method.Food and environmental virology · 2025Article
- Article
- Prevalence of BK and JC Polyomaviruses among Patients with Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Sources, fates and treatment strategies of typical viruses in urban sewage collection/treatment systems: A review.Desalination · 2022Article
- Assessment of Microbiological Quality of Fresh Vegetables and Oysters Produced in Buenos Aires Province, Argentina.Food and environmental virology · 2021Article
- Comparative Evaluation of In-House and Commercial Real-Time PCR Methods for the Detection of the BK and JC Viruses in Clinical Samples.Journal of laboratory physicians · 2020Article
- Pathogenic viruses: Molecular detection and characterization.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020Review
- Development of a Nucleic Acid Lateral Flow Immunoassay for the Detection of Human Polyomavirus BK.Diagnostics (Basel, Switzerland) · 2020Article
- Polyomaviruses shedding in stool of patients with hematological disorders: detection analysis and study of the non-coding control region's genetic variability.Medical microbiology and immunology · 2019Article
- SV40 seroprevalence in two Latin American countries involved in field trials of candidate oral poliovaccines.The Journal of infection · 2019Article
- Association Between Simian Virus 40 and Human Tumors.Frontiers in oncology · 2019Review
- Human polyomaviruses and cancer: an overview.Clinics (Sao Paulo, Brazil) · 2018Review
- Viral microRNA effects on persistent infection of human lymphoid cells by polyomavirus SV40.PloS one · 2018Article
- Editorial: Immune Control of JC Virus Infection and Immune Failure during Progressive Multifocal Leukoencephalopathy.Frontiers in immunology · 2017Article
- Detection of Malawi polyomavirus sequences in secondary lymphoid tissues from Italian healthy children: a transient site of infection.Virology journal · 2016Article
- Fecal Polyomavirus Excretion in Infancy.Journal of the Pediatric Infectious Diseases Society · 2016Article
- Review
- Evaluation of the Gastrointestinal Tract as Potential Route of Primary Polyomavirus Infection in Mice.PloS one · 2016Article
- The Fecal Virome of Children with Hand, Foot, and Mouth Disease that Tested PCR Negative for Pathogenic Enteroviruses.PloS one · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundInfection with BK virus (BKV) generally occurs early during life, but its mode of transmission has not been clearly defined. We tested the hypothesis that polyomavirus shedding in stool may be a source of BKV exposure.METHODS. Pediatric stool and rectal swab samples were tested for the presence of polyomavirus DNA by a polymerase chain reaction (PCR) assay that could detect a conserved region in the large T antigen gene of BKV, JC virus (JCV), and simian virus 40 (SV40). The specific viruses detected by this assay were confirmed by DNA sequence analysis of the PCR amplicons.Results. Of 120 samples collected from 99 patients, 54 (45.0%) were positive for polyomavirus DNA. Of the 99 patients, 46 (46.5%) had at least 1 positive sample, with 38 (38.4%) positive for BKV and 8 (8.1%) positive for SV40. JCV was not detected. There was no association between polyomavirus fecal shedding and age, sex, race/ethnicity, immune status, or symptoms of gastrointestinal disease in the children studied. The BKV strains detected displayed polymorphisms in the T antigen sequence.Conclusions. Polyomaviruses are frequently present in stool samples from hospitalized children. These findings suggest that fecal-oral transmission of BKV may play a role in the ubiquity of infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.