ArticlePlanta2005
Thaxtomin A induces programmed cell death in Arabidopsis thaliana suspension-cultured cells.
Article in Planta, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 91 citations in OpenAlex.
- Interaction of an Oomycete Nep1-like Cytolysin with Natural and Plant Cell-Mimicking Membranes.The Journal of membrane biology · 2025Article
- The Silencing of theInternational journal of molecular sciences · 2025Article
- Proteomics fingerprinting reveals importance of iron and oxidative stress inFrontiers in microbiology · 2024Article
- Apoptotic-like PCD inducing HRC gene when silenced enhances multiple disease resistance in plants.Scientific reports · 2022Article
- ThePlants (Basel, Switzerland) · 2022Article
- Plant Cell Cultures as a Tool to Study Programmed Cell Death.International journal of molecular sciences · 2021Review
- Habituation to thaxtomin A increases resistance to common scab in 'Russet Burbank' potato.PloS one · 2021Article
- Auxin protects Arabidopsis thaliana cell suspension cultures from programmed cell death induced by the cellulose biosynthesis inhibitors thaxtomin A and isoxaben.BMC plant biology · 2019Article
- Reactive Oxygen Species Alleviate Cell Death Induced by Thaxtomin A inPlants (Basel, Switzerland) · 2019Article
- The occurrence of potato common scab correlates with the community composition and function of the geocaulosphere soil microbiome.Microbiome · 2019Article
- The Plant Pathogenic BacteriumFrontiers in microbiology · 2019Article
- Article
- Resistance to Streptomyces turgidiscabies in potato involves an early and sustained transcriptional reprogramming at initial stages of tuber formation.Molecular plant pathology · 2016Article
- Taxonomy, Physiology, and Natural Products of Actinobacteria.Microbiology and molecular biology reviews : MMBR · 2016Review
- Mechanisms of thaxtomin A-induced root toxicity revealed by a thaxtomin A sensitive Arabidopsis mutant (ucu2-2/gi-2).Plant cell reports · 2016Article
- Winter wheat cells subjected to freezing temperature undergo death process with features of programmed cell death.Protoplasma · 2014Article
- Article
- Enhanced resistance to the cellulose biosynthetic inhibitors, thaxtomin A and isoxaben in Arabidopsis thaliana mutants, also provides specific co-resistance to the auxin transport inhibitor, 1-NPA.BMC plant biology · 2013Article
- Osmosensitive changes of carbohydrate metabolism in response to cellulose biosynthesis inhibition.Plant physiology · 2012Article
- Habituation to thaxtomin A in hybrid poplar cell suspensions provides enhanced and durable resistance to inhibitors of cellulose synthesis.BMC plant biology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thaxtomin A is the main phytotoxin produced by Streptomyces scabiei, the causative agent of common scab disease of potato. Pathogenicity of S. scabiei is dependent on the production of thaxtomin A which is required for the development of disease symptoms, such as growth inhibition and cell death. We investigated whether thaxtomin A-induced cell death was similar to the hypersensitive cell death that often occurs in response to specific pathogens or phytotoxins during the so-called hypersensitive response (HR). We demonstrated that thaxtomin A induced in Arabidopsis thaliana suspension-cultured cells a genetically controlled cell death that required active gene expression and de novo protein synthesis, and which involved fragmentation of nuclear DNA, a characteristic hallmark of apoptosis. The thaxtomin A-induced form of programmed cell death (PCD) was not a typical HR, since defence responses generally preceding or associated with the HR, such as rapid medium alkalization, oxidative burst and expression of defence-related genes PR1 and PDF1.2, were not observed in plant cells following addition of thaxtomin A. Thaxtomin A has been shown to inhibit cellulose biosynthesis (Scheible et al. in Plant Cell 15:1781, 2003). We showed that isoxaben, a specific inhibitor of cellulose biosynthesis, also induced in Arabidopsis cell suspensions a PCD similar to that induced by thaxtomin A. These data suggested that rapid changes in the plant cell wall composition and organization can induce PCD in plant cells. We discuss how rapid inhibition of cellulose biosynthesis may trigger this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.