ReviewJournal of muscle research and cell motility2005
Age-dependence of the spontaneous activity of the rat urinary bladder.
Review in Journal of muscle research and cell motility, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder.Frontiers in physiology · 2018Article
- Article
- Article
- Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras.PloS one · 2015Article
- Bladder smooth muscle strip contractility as a method to evaluate lower urinary tract pharmacology.Journal of visualized experiments : JoVE · 2014Article
- Article
- Urinary bladder function in conscious rat pups: a developmental study.American journal of physiology. Renal physiology · 2012Article
- A possible role of the cholinergic and purinergic receptor interaction in the regulation of the rat urinary bladder function.Journal of muscle research and cell motility · 2012Article
- Sex- and age-related changes in connexin 43 expression in normal rat bladder.International neurourology journal · 2011Article
- Gastrodia elata decreases isoprenaline potency and enhances spontaneous phasic activity in the rat detrusor.International journal of physiology, pathophysiology and pharmacology · 2011Article
- An exploration of the control of micturition using a novel in situ arterially perfused rat preparation.Frontiers in neuroscience · 2011Article
- Potential for control of detrusor smooth muscle spontaneous rhythmic contraction by cyclooxygenase products released by interstitial cells of Cajal.Journal of cellular and molecular medicine · 2009Article
- Immunohistochemical study of the pre- and postnatal innervation of the dog lower urinary tract: morphological aspects at the basis of the consolidation of the micturition reflex.Veterinary research communications · 2008Article
- Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists.American journal of physiology. Renal physiology · 2007Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Abnormal mechanical function of the bladder is manifested in a number of ways including higher frequency of involuntary detrusor contractions associated with reduced compliance of the bladder that is responsible for an increase in intraluminal pressure during filling. There are basically two ways to approach experimentally these problems: (1) by studying the neural control of the lower urinary tract function, and (2) by measuring the properties of smooth muscle cells in the bladder wall. Studies on smooth muscle function often do not take the origin of smooth muscle cells into account i.e., whether they were harvested from normal or overactive bladders. Although, this simplistic view may be beneficial to understanding the generation of the spontaneous activity of the bladder, however, it does not sufficiently explain the cell-to-cell propagation of the spontaneous smooth muscle activity. The spontaneous activity of smooth muscle is an important factor that works against the bladder compliance in the filling phase, and may inversely affect the neurally evoked response during micturition. The intensity of spontaneous activity is the age-dependent; it is high in neonatal bladders it is small or almost non-existent in adults and reemerges in older bladders. This review focuses on these age-dependent alterations of spontaneous bladder contractions and describes the possible mechanisms which may have important role in regulating the spontaneous contractions using the rat as an animal model.
Indexed as
Identifiers
16025204What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.