ArticleJournal of molecular evolution1992
Insect muscle actins differ distinctly from invertebrate and vertebrate cytoplasmic actins.
Article in Journal of molecular evolution, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 68 citations in OpenAlex.
- Electroporation-mediated functional analysis method of genes in the giant insect Trypoxylus dichotomus.Scientific reports · 2025Article
- Whole genome analysis of a schistosomiasis-transmitting freshwater snail.Nature communications · 2017Article
- How the mountain pine beetle (Dendroctonus ponderosae) breached the Canadian Rocky Mountains.Molecular biology and evolution · 2014Article
- Structural and functional characterization of the actin-1 gene promoter from the Antheraea pernyi (Lepidoptera: Saturniidae).Journal of insect science (Online) · 2014Article
- Molecular architecture of muscles in an acoel and its evolutionary implications.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2011Article
- Transcription of muscle actin genes by a nuclear form of mitochondrial RNA polymerase.PloS one · 2011Article
- Analysis of tarantula skeletal muscle protein sequences and identification of transcriptional isoforms.BMC genomics · 2009Article
- Induction of actin gene expression in the mosquito midgut by blood ingestion correlates with striking changes of cell shape.Journal of insect physiology · 2007Article
- Actin cytoskeleton and small heat shock proteins: how do they interact?Cell stress & chaperones · 2002Review
- Detection and quantification of infectious hypodermal and hematopoietic necrosis virus and white spot virus in shrimp using real-time quantitative PCR and SYBR Green chemistry.Journal of clinical microbiology · 2001Article
- Structural comparisons of muscle and nonmuscle actins give insights into the evolution of their functional differences.Journal of molecular evolution · 1997Article
- Codon bias in actin multigene families and effects on the reconstruction of phylogenetic relationships.Journal of molecular evolution · 1995Article
- Evolution of actin gene families of sea urchins.Journal of molecular evolution · 1994Article
- Molecular genetics of actin function.The Biochemical journal · 1993Review
- Evolution of the chordate muscle actin gene.Journal of molecular evolution · 1993Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invertebrate actins resemble vertebrate cytoplasmic actins, and the distinction between muscle and cytoplasmic actins in invertebrates is not well established as for vertebrate actins. However, Bombyx and Drosophila have actin genes specifically expressed in muscles. To investigate if the distinction between muscle and cytoplasmic actins evidenced by gene expression analysis is related to the sequence of corresponding genes, we compare the sequences of actin genes of these two insect species and of other Metazoa. We find that insect muscle actins form a family of related proteins characterized by about 10 muscle-specific amino acids. Insect muscle actins have clearly diverged from cytoplasmic actins and form a monophyletic group emerging from a cluster of closely related proteins including insect and vertebrate cytoplasmic actins and actins of mollusc, cestode, and nematode. We propose that muscle-specific actin genes have appeared independently at least twice during the evolution of animals: insect muscle actin genes have emerged from an ancestral cytoplasmic actin gene within the arthropod phylum, whereas vertebrate muscle actin genes evolved within the chordate lineage as previously described.
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