Evidence map›Paper›PMID 16023210›Full record

ReviewMolecular immunology2006

Clinical manifestations of mannan-binding lectin deficiency.

S Thiel, P D Frederiksen, J C Jensenius

Open access · greenAbstract readReview
In one paragraph

Review in Molecular immunology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 196 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2012
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Collectins: Innate Immune Pattern Recognition Molecules.Advances in experimental medicine and biology · 2020
    Review
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S ThielDepartment of Medical Microbiology and Immunology, University of Aarhus, DK8000 Denmark. st@microbiology.au.dk
P D Frederiksen
J C Jensenius
Aarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency may lead to disease. With examples, this review illustrates the diversity of results obtained so far.

Indexed as

Immunity, InnateAnimalsAutoimmune DiseasesBlood ProteinsHumansInfectionsMannose-Binding LectinMiceMice, KnockoutSystemic Inflammatory Response SyndromeVascular DiseasesBlood ProteinsMannose-Binding LectinMBL2 protein, human

Identifiers

PMID16023210
PMCPMC7132399
OpenAlexW2166071749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.