Evidence map›Paper›PMID 16013973›Full record

ReviewExpert review of molecular diagnostics2005

Miniaturized detection technology in molecular diagnostics.

Larry J Kricka, Jason Y Park, Sam F Y Li, Paolo Fortina

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of molecular diagnostics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Larry J KrickaDepartment of Pathology & Laboratory Medicine, University of Pennsylvania School of Medicine, 7.103 Founders Pavilion, 3400 Spruce Street, Philadelphia, PA 19104, USA. kricka@mail.med.upenn.edu
Jason Y Park
Sam F Y Li
Paolo Fortina
Hospital of the University of Pennsylvania · USNational University of Singapore · SGSapienza University of Rome · ITUniversity of Pennsylvania · US

Funding

FOUR COLOR ARRAY BOUND SNP/MUTATION DETECTION IN CANCERR33CA083220 · NCI · THOMAS JEFFERSON UNIVERSITY · PI FORTINA, PAOLO M · 2002 to 2004
$1.8M
PARALLEL AND HIGH THROUGHPUT MICROSAMPLE PROCESSINGR01CA078848 · NCI · UNIVERSITY OF PENNSYLVANIA · PI WILDING, PETER · 1999 to 2002
$954k
NCI NIH HHS R01-CA 78848-04NCI NIH HHS R33-CA83220
6 · The paper itself

Abstract

Miniaturization of genetic tests represents the convergence of molecular biology and engineering and is leading to a new class of small analyzers and test systems for genetic testing with improved analytical characteristics. Miniaturization initially focused on devices that contained micrometer-sized features designed for a particular analytical purpose (e.g., filters for cell isolation and chips for capillary electrophoresis). Now, the focus is shifting to analytical applications based on nano-sized objects such as nanotubes, nanochannels, nanoparticles, nanopores and nanocapacitors. These nanofabricated objects provide new tools for sequencing of nucleic acids and rapid, multiplexed, nucleic acid detection.

Indexed as

AnimalsElectrochemistryElectrophoresis, CapillaryHumansMicroarray AnalysisMiniaturizationMolecular Diagnostic TechniquesNucleic AcidsNucleic Acids

Identifiers

PMID16013973
PMCPMC7105751
OpenAlexW2139300753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.