Evidence map›Paper›PMID 16012515›Full record

ReviewNature reviews. Microbiology2005

Going against the grain: chemotaxis and infection in Vibrio cholerae.

Susan M Butler, Andrew Camilli

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 400 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Light-activated cAMP signaling controls sodium-driven motility inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Collective bacterial condensation is fundamentally constrained by the emergence of active turbulence.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Cell-body curvature modulates stall frequency to enhancebioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Nitric oxide promotes rapid development of motility to accelerate biofilm dispersal inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Non-toxigenicArchive of clinical cases · 2025
    Review
  17. mBio · 2024
    Article
  18. Article
  19. Benzenesulfonamide derivatives asJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  20. Article

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Susan M ButlerTufts University School of Medicine, Department of Molecular Biology and Microbiology, 136 Harrison Avenue, Boston, Massachusetts 02111, USA.
Andrew Camilli
Tufts University · US

Funding

Study of transmissible forms of Vibrio CholeraeR01AI055058 · NIAID · TUFTS UNIVERSITY BOSTON · PI CAMILLI, ANDREW · 2003 to 2019
$5.8M
Phage Resistance in Emergent Vibrio cholerae and Phage Prophylaxis of CholeraR37AI055058 · NIAID · TUFTS UNIVERSITY BOSTON · PI Andrew Camilli · 2020 to 2026
$3.4M
NIAID NIH HHS R01 AI055058NIAID NIH HHS R37 AI055058
6 · The paper itself

Abstract

Chemotaxis is the process by which motile cells move in a biased manner both towards favourable and away from unfavourable environments. The requirement of this process for infection has been examined in several bacterial pathogens, including Vibrio cholerae. The single polar flagellum of Vibrio species is powered by a sodium-motive force across the inner membrane, and can rotate to produce speeds of up to 60 cell-body lengths (approximately 60microm) per second. Investigating the role of the chemotactic control of rapid flagellar motility during V. cholerae infection has revealed some unexpected and intriguing results.

Indexed as

ChemotaxisCholeraFlagellaHumansVibrio choleraeVirulence

Identifiers

PMID16012515
PMCPMC2799996
OpenAlexW2052451249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.