ArticlePlant physiology2005
Effects of calreticulin on viral cell-to-cell movement.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
80 citing papers in PubMed, 171 citations in OpenAlex.
- Role of Plasmodesmata During Plant-Pathogen Interactions.The plant pathology journal · 2026Review
- Transcriptomic Profiling of Host Responses Underlying Synergistic Interaction Between the Phloem-Limited Brassica Yellows Virus and Pea Enation Mosaic Virus 2 inPlants (Basel, Switzerland) · 2026Article
- Loss-of-Function of Two PD-Associated Proteins Confers Resistance to Rice Stripe Virus.Molecular plant pathology · 2025Article
- Silencing of Putative Plasmodesmata-Associated GenesPlants (Basel, Switzerland) · 2025Article
- Tobacco Mosaic Virus Movement: From Capsid Disassembly to Transport Through Plasmodesmata.Viruses · 2025Review
- Cellular Partners of Tobamoviral Movement Proteins.International journal of molecular sciences · 2025Review
- Identification of the CaCRT gene family and function of CaCRT1 under low-temperature stress in pepper (Capsicum annuum L.).Scientific reports · 2025Article
- The roles of movement and coat proteins in the transport of tobamoviruses between plant cells.Frontiers in plant science · 2025Review
- Plant-specific calreticulin is localized in the nuclei of highly specialized cells in the pistil-new observations for an old hypothesis.Protoplasma · 2024Article
- Plasmodesmata Function and Callose Deposition in Plant Disease Defense.Plants (Basel, Switzerland) · 2024Review
- Calcium signaling: an emerging player in plant antiviral defense.Journal of experimental botany · 2024Article
- Comprehensive genomic characterization and expression analysis of calreticulin gene family in tomato.Frontiers in plant science · 2024Article
- The Role of Plant Latex in Virus Biology.Viruses · 2023Review
- A viral movement protein co-opts endoplasmic reticulum luminal-binding protein and calreticulin to promote intracellular movement.Plant physiology · 2023Article
- A novel cellular factor ofFrontiers in plant science · 2023Article
- Variability, Functions and Interactions of Plant Virus Movement Proteins: What Do We Know So Far?Microorganisms · 2021Review
- Review
- Genome Editing for Plasmodesmal Biology.Frontiers in plant science · 2021Review
- Plasmodesmata-Involved Battle Against Pathogens and Potential Strategies for Strengthening Hosts.Frontiers in plant science · 2021Review
- Loss of function of CRT1a (calreticulin) reduces plant susceptibility to Verticillium longisporum in both Arabidopsis thaliana and oilseed rape (Brassica napus).Plant biotechnology journal · 2020Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell-to-cell tobacco mosaic virus movement protein (TMV MP) mediates viral spread between the host cells through plasmodesmata. Although several host factors have been shown to interact with TMV MP, none of them coresides with TMV MP within plasmodesmata. We used affinity purification to isolate a tobacco protein that binds TMV MP and identified it as calreticulin. The interaction between TMV MP and calreticulin was confirmed in vivo and in vitro, and both proteins were shown to share a similar pattern of subcellular localization to plasmodesmata. Elevation of the intracellular levels of calreticulin severely interfered with plasmodesmal targeting of TMV MP, which, instead, was redirected to the microtubular network. Furthermore, in TMV-infected plant tissues overexpressing calreticulin, the inability of TMV MP to reach plasmodesmata substantially impaired cell-to-cell movement of the virus. Collectively, these observations suggest a functional relationship between calreticulin, TMV MP, and viral cell-to-cell movement.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.