ArticleEuropean journal of applied physiology2005
Changes in erythropoietin and haemoglobin concentrations in response to saturation diving.
Article in European journal of applied physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Acute short-term hyperoxia followed by mild hypoxia does not increase EPO production: resolving the "normobaric oxygen paradox".European journal of applied physiology · 2012Trial
- Assessment of Diagnostic Tools to Detect Acute Gas Bubble Disease in Atlantic Salmon (Salmo salar L.).Journal of fish diseases · 2025Article
- Shifts in the Oral Microbiota During a Four-Week Commercial Saturation Dive to 200 Meters.Frontiers in physiology · 2021Article
- Biomarkers of neuronal damage in saturation diving-a controlled observational study.European journal of applied physiology · 2020Observational
- Effects of recreational scuba diving on erythropoiesis-"normobaric oxygen paradox" or "plasma volume regulation" as a trigger for erythropoietin?European journal of applied physiology · 2020Article
- Hemoglobin During and Following a 4-Week Commercial Saturation Dive to 200 m.Frontiers in physiology · 2019Article
- Commercial Divers' Subjective Evaluation of Saturation.Frontiers in psychology · 2018Article
- Blood Gene Expression and Vascular Function Biomarkers in Professional Saturation Diving.Frontiers in physiology · 2018Article
- Hemoglobin and Erythropoietin After Commercial Saturation Diving.Frontiers in physiology · 2018Article
- Oxygen Toxicity and Special Operations Forces Diving: Hidden and Dangerous.Frontiers in psychology · 2017Review
- Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: recommendations for saturation divers.Extreme physiology & medicine · 2016Review
- No changes in lung function after a saturation dive to 2.5 MPa with intermittent reduction in Po2 during decompression.European journal of applied physiology · 2006Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A reduction in haemoglobin concentration is consistently reported after deep saturation dives. This may be due to a downregulation of erythropoietin (EPO) concentration or to a toxic effect of the hyperoxia associated with the dives resulting in an increased destruction rate of erythrocytes. In this study haemoglobin concentration, blood cell counts, serum ferritin, bilirubin, haptoglobin and EPO concentrations were measured before, during and after a 19 day saturation dive to 240 m. The partial pressure of oxygen (PO(2)) was 35-70 kPa during the 7 day compression and bottom phase, and 30-50 kPa during the 12 day decompression phase. There was a reduction in EPO concentration from 8.4+/-1.4 (mean +/- 1SD) to 6.3 +/- 1.9 U.L(-1) on Dive day 2. On Dive days 7 and 17 EPO concentrations were not significantly different from baseline despite the continued exposure to hyperoxia. Immediately after the dive and return to a normoxic environment there was an increase in the EPO concencentration to 14.5 +/- 4.7 U.L(-1). Haemoglobin concentration, erythrocyte and reticulocyte counts were decreased at the end of the dive, and there was an increase in serum ferritin. There were no changes in bilirubin or haptoglobin concentrations indicative of haemolysis. It appears that the change in PO(2), rather than the sustained exposure to a hyperoxic environment, induces the changes in the EPO concentrations and erythropoietic activity.
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Registered trials
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