ReviewChromosoma2005
Molecular cytogenetics in haematological malignancy: current technology and future prospects.
Review in Chromosoma, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 48 citations in OpenAlex.
- Chromosome Karyotyping in Hematological Malignancies: Current Status and Future Directions.Current medical science · 2026Review
- Overview on Aneuploidy in Childhood B-Cell Acute Lymphoblastic Leukemia.International journal of molecular sciences · 2023Review
- Multiplex ligation-dependent probe amplification identifies copy number changes in normal and undetectable karyotype MDS patients.Annals of hematology · 2021Article
- Article
- Cytogenetic Profile andClinical Medicine Insights. Oncology · 2017Article
- Article
- High Throughput FISH Analysis: A New, Sensitive Option For Evaluation of Hematological Malignancies.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2013Article
- Genome Fusion Detection: a novel method to detect fusion genes from SNP-array data.Bioinformatics (Oxford, England) · 2013Article
- Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia.Genome research · 2012Article
- Mechanisms and impacts of chromosomal translocations in cancers.Frontiers of medicine · 2012Review
- Array comparative genomic hybridization and cytogenetic analysis in pediatric acute leukemias.Current oncology (Toronto, Ont.) · 2011Article
- Molecular cytogenetics in translational oncology: when chromosomes meet genomics.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2008Review
- Preservation of skin DNA for oligonucleotide array CGH studies: a feasibility study.Archives of dermatological research · 2007Article
- Comparative genomic hybridization arrays in clinical pathology: progress and challenges.Molecular diagnosis & therapy · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cytogenetics has played a pivotal role in haematological malignancy, both as an aid to diagnosis and in identifying recurrent chromosomal rearrangements, an essential prerequisite to identifying genes involved in leukaemia and lymphoma pathogenesis. In the late 1980s, a series of technologies based around fluorescence in situ hybridisation (FISH) revolutionised the field. Interphase FISH, multiplex-FISH (M-FISH, SKY) and comparative genomic hybridisation (CGH) have emerged as the most significant of these. More recently, microarray technologies have come to prominence. In the acute leukaemias, the finding of characteristic gene expression signatures corresponding to biological subgroups has heralded gene expression profiling as a possible future alternative to current cytogenetic and morphological methods for diagnosis. In the lymphomas, high-resolution array CGH has successfully identified new regions of deletion and amplification, providing the prospect of disease-specific arrays.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.