ArticleMicrobial ecology2005
Medium N:P ratios and specific growth rate comodulate microcystin and protein content in Microcystis aeruginosa PCC7806 and M. aeruginosa UV027.
Article in Microbial ecology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Impact of high temperature and UVR exposure on the microcystin production and mcyB gene expression in the cyanobacterium Microcystis aeruginosa.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Review
- Study of the growth and biochemical composition of 20 species of cyanobacteria cultured in cylindrical photobioreactors.Microbial cell factories · 2023Article
- Article
- Article
- Effects of microcystin-producing and microcystin-freeMicrocystis aeruginosa on enzyme activity and nutrient content in the rotifer Brachionus calyciflorus.Environmental science and pollution research international · 2017Article
- Life strategy and grazing intensity responses of Brachionus calyciflorus fed on different concentrations of microcystin-producing and microcystin-free Microcystis aeruginosa.Scientific reports · 2017Article
- Microcystin Biosynthesis andBioMed research international · 2016Article
- Effects of artemisinin sustained-release granules on mixed alga growth and microcystins production and release.Environmental science and pollution research international · 2015Article
- Hormesis effects of amoxicillin on growth and cellular biosynthesis of Microcystis aeruginosa at different nitrogen levels.Microbial ecology · 2015Article
- Cellular and transcriptional responses in Microcystis aeruginosa exposed to two antibiotic contaminants.Microbial ecology · 2015Article
- Effects of linear alkylbenzene sulfonate on the growth and toxin production of Microcystis aeruginosa isolated from Lake Dianchi.Environmental science and pollution research international · 2015Article
- Review
- Effects of allelochemical extracted from water lettuce (Pistia stratiotes Linn.) on the growth, microcystin production and release of Microcystis aeruginosa.Environmental science and pollution research international · 2013Article
- Model Simulation of Diurnal Vertical Migration Patterns of Different-Sized Colonies ofEnvironmental engineering science · 2013Article
- Article
- Influence of cultivation parameters on growth and microcystin production of Microcystis aeruginosa (Cyanophyceae) isolated from Lake Chao (China).Microbial ecology · 2012Article
- Microcystin-LR synthesis as response to nitrogen: transcriptional analysis of the mcyD gene in Microcystis aeruginosa PCC7806.Ecotoxicology (London, England) · 2010Article
- Spatiotemporal variations in microcystin concentrations and in the proportions of microcystin-producing cells in several Microcystis aeruginosa populations.Applied and environmental microbiology · 2010Article
- Temporal variations in the dynamics of potentially microcystin-producing strains in a bloom-forming Planktothrix agardhii (Cyanobacterium) population.Applied and environmental microbiology · 2008Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatotoxin production in cyanobacteria has been shown to correlate to external stimuli such as light and nutrient concentrations and ratios, although conflicting results have been reported. Specific growth rates and protein and microcystin content of M. aeruginosa PCC7806 and M. aeruginosa UV027 were determined under nonlimiting batch culture conditions for a range of medium nitrogen and phosphorous atomic ratios. Both strains exhibited a similar optimal medium N:P ratio for increased cellular microcystin levels. Additionally, total cellular protein content and intracellular microcystin content were significantly correlated to each other (r2 = 0.81, p < 0.001). Microcystin and protein content increased considerably as the maximum specific growth rate for the experimental conditions was reached. The significant correlation of cellular protein and microcystin content and their relative increase with increasing specific growth rate, within defined ranges of medium N:P ratios, suggest a close association between microcystin production and N:P ratio-dependent assimilation of nitrogen, and resulting total cellular protein levels, which may be further modulated by specific growth rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.