Evidence map›Paper›PMID 16002656›Full record

ArticleEukaryotic cell2005

Galactomannoproteins of Aspergillus fumigatus.

W Morelle, M Bernard, J-P Debeaupuis, M Buitrago, M Tabouret, J-P Latgé

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Eukaryotic cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 96 citations in OpenAlex.

  1. Article
  2. GalInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Galactomannan Produced byJournal of fungi (Basel, Switzerland) · 2020
    Review
  5. Aspergillus fumigatus and Aspergillosis in 2019.Clinical microbiology reviews · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Urine Antigen Detection as an Aid to Diagnose Invasive Aspergillosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  10. Diversity of Cell Wall Related Proteins in Human Pathogenic Fungi.Journal of fungi (Basel, Switzerland) · 2017
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

W MorelleUnité des Aspergillus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France.
M Bernard
J-P Debeaupuis
M Buitrago
M Tabouret
J-P Latgé
Institut Pasteur · FRBio-Rad (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Galactofuranose-containing molecules have been repeatedly shown to be important antigens among human fungal pathogens, including Aspergillus fumigatus. Immunogenic galactofuran determinants have been poorly characterized chemically, however. We reported here the characterization of two glycoproteins of A. fumigatus with an N-glycan containing galactofuranose. These proteins are a phospholipase C and a phytase. Chemical characterization of the N-glycan indicates that it is a mixture of Hex(5-13)HexNAc(2) oligosaccharides, the major molecular species corresponding to Hex(6-8)HexNAc(2). The N-glycan contained one galactofuranose unit that was in a terminal nonreducing position attached to the 2 position of Man. This single terminal nonreducing galactofuranose is essential for the immunoreactivity of the N-glycans assessed either with a monoclonal antibody that recognizes a tetra-beta-1,5-galactofuran chain of galactomannan or with Aspergillus-infected patient sera.

Indexed as

6-Phytasealpha-MannosidaseAntibodies, FungalAntigens, FungalAspergillosisAspergillus fumigatusEnzyme-Linked Immunosorbent AssayGas Chromatography-Mass SpectrometryHumansHydrofluoric AcidMembrane GlycoproteinsPolysaccharidesSensitivity and SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationType C Phospholipases6-Phytasealpha-MannosidaseAntibodies, FungalAntigens, Fungalgalactomannoprotein, Aspergillus fumigatusHydrofluoric AcidMembrane GlycoproteinsPolysaccharidesType C Phospholipases

Identifiers

PMID16002656
PMCPMC1168957
OpenAlexW2139193265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.