ArticleAmerican journal of human genetics2005
A genomewide scan for intelligence identifies quantitative trait loci on 2q and 6p.
Article in American journal of human genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 131 citations in OpenAlex.
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- Expression Analysis of Ermin and Listerin E3 Ubiquitin Protein Ligase 1 Genes in Autistic Patients.Frontiers in molecular neuroscience · 2021Article
- Genetic and epigenetic methylation defects and implication of the ERMN gene in autism spectrum disorders.Translational psychiatry · 2016Article
- Cryptic de novo deletion at 2q23.3-q24.1 in a patient with intellectual disability.Journal of genetics · 2016Article
- Zinc finger protein 804A (ZNF804A) and verbal deficits in individuals with autism.Journal of psychiatry & neuroscience : JPN · 2014Article
- Epigenetic analysis of neurocognitive development at 1 year of age in a community-based pregnancy cohort.Behavior genetics · 2014Article
- Genetic effects on the cerebellar role in working memory: same brain, different genes?NeuroImage · 2014Article
- The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2013Article
- No effect of genome-wide copy number variation on measures of intelligence in a New Zealand birth cohort.PloS one · 2013Article
- Triggers for autism: genetic and environmental factors.Journal of central nervous system disease · 2012Article
- Genetic variation in cholinergic muscarinic-2 receptor gene modulates M2 receptor binding in vivo and accounts for reduced binding in bipolar disorder.Molecular psychiatry · 2011Article
- The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2011Article
- Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.PloS one · 2011Article
- Genome-scan for IQ discrepancy in autism: evidence for loci on chromosomes 10 and 16.Human genetics · 2011Article
- Reduced dysbindin expression mediates N-methyl-D-aspartate receptor hypofunction and impaired working memory performance.Biological psychiatry · 2011Article
- A three-stage genome-wide association study of general cognitive ability: hunting the small effects.Behavior genetics · 2010Article
- A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry.Schizophrenia research · 2010Article
- QTL analysis for resistance to foliar damage caused by Thrips tabaci and Frankliniella schultzei (Thysanoptera: Thripidae) feeding in cowpea [Vigna unguiculata (L.) Walp.].Molecular breeding : new strategies in plant improvement · 2010Article
- Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence.Neuroscience · 2009Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Between 40% and 80% of the variation in human intelligence (IQ) is attributable to genetic factors. Except for many rare mutations resulting in severe cognitive dysfunction, attempts to identify these factors have not been successful. We report a genomewide linkage scan involving 634 sibling pairs designed to identify chromosomal regions that explain variation in IQ. Model-free multipoint linkage analysis revealed evidence of a significant quantitative-trait locus for performance IQ at 2q24.1-31.1 (LOD score 4.42), which overlaps the 2q21-33 region that has repeatedly shown linkage to autism. A second region revealed suggestive linkage for both full-scale and verbal IQs on 6p25.3-22.3 (LOD score 3.20 for full-scale IQ and 2.33 for verbal IQ), overlapping marginally with the 6p22.3-21.31 region implicated in reading disability and dyslexia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.