Evidence map›Paper›PMID 16000837›Full record

ArticleApplied and environmental microbiology2005

Identification and functional analysis of Escherichia coli cysteine desulfhydrases.

Naoki Awano, Masaru Wada, Hirotada Mori, Shigeru Nakamori, Hiroshi Takagi

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 160 citations in OpenAlex.

  1. Review
  2. iScience · 2026
    Article
  3. Review
  4. Pharmacomicrobiomics.Clinical pharmacology and therapeutics · 2025
    Review
  5. Review
  6. Article
  7. Experimental evolution ofMicrobiology spectrum · 2025
    Article
  8. Article
  9. Review
  10. Effect of HArchives of microbiology · 2024
    Article
  11. Review
  12. Review
  13. Regulation of Cysteine Homeostasis and Its Effect onInternational journal of molecular sciences · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Role of Hydrogen Sulfide in Inflammatory Bowel Disease.Antioxidants (Basel, Switzerland) · 2023
    Review
  18. Review
  19. Review
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Naoki AwanoDepartment of Bioscience, Fukui Prefectural University, 4-1-1 Kenjojima, Matsuoka-cho, Fukui 910-1195, Japan.
Masaru Wada
Hirotada Mori
Shigeru Nakamori
Hiroshi Takagi
Fukui Prefectural University · JPNara Institute of Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Escherichia coli, three additional proteins having L-cysteine desulfhydrase activity were identified as O-acetylserine sulfhydrylase-A, O-acetylserine sulfhydrylase-B, and MalY protein, in addition to tryptophanase and cystathionine beta-lyase, which have been reported previously. The gene disruption for each protein was significantly effective for overproduction of L-cysteine and L-cystine. Growth phenotype and transcriptional analyses suggest that tryptophanase contributes primarily to L-cysteine degradation.

Indexed as

Cystathionine gamma-LyaseCysteineCysteine SynthaseCystineEscherichia coliEscherichia coli ProteinsGene DeletionLyasesRepressor ProteinsTryptophanasecystathionine beta-lyaseCystathionine gamma-LyaseCysteineCysteine SynthaseCystineEscherichia coli ProteinsLyasesMalY protein, E coliRepressor ProteinsTryptophanase

Identifiers

PMID16000837
PMCPMC1169034
OpenAlexW2097691801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.