Evidence map›Paper›PMID 16000504›Full record

ArticleJournal of clinical microbiology2005

Fatal reactivation of postnatal cytomegalovirus infection with rapid emergence of ganciclovir resistance in an infant after allogeneic stem cell transplantation.

Sebastian Voigt, Detlef Michel, Olivia Kershaw, Jörn-Sven Kühl, Thomas Mertens, Wolfram Ebell, Helga Meisel

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Bilateral cytomegalovirus retinitis in a healthy infant.Journal of current ophthalmology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sebastian VoigtPediatric Bone Marrow Transplant Unit, Charité Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany. sebastian.voigt@charite.de
Detlef Michel
Olivia Kershaw
Jörn-Sven Kühl
Thomas Mertens
Wolfram Ebell
Helga Meisel
Charité - Universitätsmedizin Berlin · DEUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) can cause serious problems after hematopoietic stem cell transplantation. The death of a pediatric transplant recipient after reactivation of a postnatal HCMV infection with bilateral retinitis and pneumonitis is described. Sequencing of the HCMV UL97 region revealed a compartment-specific mutation (H520Q) in urine conferring ganciclovir resistance.

Indexed as

Virus ActivationAntiviral AgentsCytomegalovirusCytomegalovirus RetinitisFatal OutcomeHematopoietic Stem Cell TransplantationHumansInfantPhosphotransferases (Alcohol Group Acceptor)PneumoniaTransplantation, HomologousAntiviral Agentsganciclovir kinasePhosphotransferases (Alcohol Group Acceptor)

Identifiers

PMID16000504
PMCPMC1169106
OpenAlexW2129743309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.