Evidence map›Paper›PMID 16000468›Full record

ArticleJournal of clinical microbiology2005

Potential secondary pathogenic role for bovine herpesvirus 4.

Gaetano Donofrio, Sandro Cavirani, Vicky van Santen, Cesidio Filippo Flammini

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Patterns of Genital TractBiomolecules · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Gammaherpesvirus infections in equids: a review.Veterinary medicine (Auckland, N.Z.) · 2015
    Review
  12. Article
  13. Virotherapy in cancer.Iranian journal of cancer prevention · 2013
    Review
  14. Article
  15. Uterine diseases in cattle after parturition.Veterinary journal (London, England : 1997) · 2008
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gaetano DonofrioDipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Facoltà di Medicina Veterinaria, via del Taglio 8, 43100 Parma, Italy. gaetano.donofrio@unipr.it
Sandro Cavirani
Vicky van Santen
Cesidio Filippo Flammini
Auburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with no clear disease association. Previous studies have demonstrated that macrophages can harbor persistent BoHV-4. We found that the addition of prostaglandin E2 (PGE2) to bovine macrophage cells persistently infected with BoHV-4 increases viral replication. Because opportunistic infection can increase PGE2 production, we propose a link between opportunistic infection, PGE2 production, and BoHV-4 replication.

Indexed as

AnimalsCattleCell Line, TumorDinoprostoneHerpesvirus 4, BovineMacrophages, PeritonealVirus LatencyVirus ReplicationDinoprostone

Identifiers

PMID16000468
PMCPMC1169148
OpenAlexW2139137351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.