Evidence map›Paper›PMID 15998615›Full record

ArticleJournal of medical Internet research2005

An Internet-based cancer clinical trials matching resource.

James M Metz, Carolyn Coyle, Courtney Hudson, Margaret Hampshire

Abstract readComparative Study
In one paragraph

Article in Journal of medical Internet research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. OCTANE: Oncology Clinical Trial Annotation Engine.JCO clinical cancer informatics · 2019
    Article
  5. Article
  6. Automatic data source identification for clinical trial eligibility criteria resolution.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2016
    Article
  7. Article
  8. Article
  9. Article
  10. Outcomes of a cancer clinical trial matching service.Journal of cancer education : the official journal of the American Association for Cancer Education · 2012
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James M MetzUniversity of Pennsylvania Cancer Center, Philadelphia, PA, USA. metz@xrt.upenn.edu
Carolyn Coyle
Courtney Hudson
Margaret Hampshire

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany patients are now accessing the Internet to obtain cancer clinical trials information. However, services offering clinical trials recruitment information have not been well defined.

objectivesThis study describes one of the first Web-based cancer clinical trials matching resources and the demographics of users who were successfully matched.

methodsOncoLink is the Internet-based educational resource managed by the University of Pennsylvania Cancer Center (UPCC) and serves between 1 and 2 million pages per month to over 385000 unique IP addresses. OncoLink launched one of the first clinical trials matching resources on the Internet that allowed patients to enter demographic data through a secure connection and be matched to clinical trials. For patients with matches to potential trials, appointments were facilitated with the principal investigators.

resultsWhile we did not keep track of patients who could not be matched, 627 patients who submitted online applications between January 2002 and April 2003 were successfully matched for potential enrollment in clinical trials. The mean age of the patient population was 56 years (range 18-88 years). Males represented 60% of the patient population, and over 90% of users were Caucasian. Most of the applications were from patients with colorectal cancer (13%), lung cancer (14%), melanoma (10%), and non-Hodgkin's lymphoma (9%).

conclusionsThis report shows that a significant number of patients are willing to use the Internet for enrolling in clinical trials. Care must be taken to reach patients from a variety of socioeconomic and racial backgrounds. This Internet resource helps to facilitate a consultation with a cancer patient who is prescreened and motivated to enroll in clinical trials.

Indexed as

InternetOnline SystemsAdultAgedAged, 80 and overClinical Trials as TopicFemaleHumansMaleMiddle AgedNeoplasmsNeoplasm StagingPatient SelectionResearch Design

Identifiers

PMID15998615
PMCPMC1550658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.