ArticleThe Plant cell2005
Novel and mechanical stress-responsive MicroRNAs in Populus trichocarpa that are absent from Arabidopsis.
Article in The Plant cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 265 papers.
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Who cites it
265 citing papers in PubMed, 596 citations in OpenAlex.
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- Ghr-miR166b-GhHB14 Pair With GhDLO1 Partner Mediates Cotton Plant Defence Against Verticillium dahliae.Molecular plant pathology · 2025Article
- COMolecules (Basel, Switzerland) · 2025Review
- miRNA in mechanobiology: The exploration needs to continue.Mechanobiology in medicine · 2024Article
- Analysis of the miR482 Gene Family in Plants.Genes · 2024Article
- Genome-Wide Identification and Characterization of miRNAs and Natural Antisense Transcripts Show the Complexity of Gene Regulatory Networks for Secondary Metabolism inInternational journal of molecular sciences · 2024Article
- Genome-Wide Identification and Functional Analysis ofInternational journal of molecular sciences · 2024Article
- Adaptive regulation of miRNAs/milRNAs in tissue-specific interaction between apple andHorticulture research · 2024Article
- Merit of integrating in situ transcriptomics and anatomical information for cell annotation and lineage construction in single-cell analyses of Populus.Genome biology · 2024Article
- The Smi-miR858a-Horticulture research · 2024Article
- Regulation of endogenous hormone and miRNA in leaves of alfalfa (Medicago sativa L.) seedlings under drought stress by endogenous nitric oxide.BMC genomics · 2024Article
- EnhancingFrontiers in plant science · 2024Article
- Regulation of plant immunity via small RNA-mediated control of NLR expression.Journal of experimental botany · 2023Article
- CottonBiology · 2023Article
- MicroRNA408 negatively regulates salt tolerance by affecting secondary cell wall development in maize.Plant physiology · 2023Article
- The PtoTCP20-miR396d-PtoGRF15 module regulates secondary vascular development in Populus.Plant communications · 2023Article
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205 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are small, noncoding RNAs that can play crucial regulatory roles in eukaryotes by targeting mRNAs for silencing. To test whether miRNAs play roles in the regulation of wood development in tree species, we isolated small RNAs from the developing xylem of Populus trichocarpa stems and cloned 22 miRNAs. They are the founding members of 21 miRNA gene families for 48 miRNA sequences, represented by 98 loci in the Populus genome. A majority of these miRNAs were predicted to target developmental- and stress/defense-related genes and possible functions associated with the biosynthesis of cell wall metabolites. Of the 21 P. trichocarpa miRNA families, 11 have sequence conservation in Arabidopsis thaliana but exhibited species-specific developmental expression patterns, suggesting that even conserved miRNAs may have different regulatory roles in different species. Most unexpectedly, the remaining 10 miRNAs, for which 17 predicted targets were experimentally validated in vivo, are absent from the Arabidopsis genome, suggesting possible roles in tree-specific processes. In fact, the expression of a majority of the cloned miRNAs was upregulated or downregulated in woody stems in a manner consistent with tree-specific corrective growth against tension and compression stresses, two constant mechanical loads in trees. Our results show that plant miRNAs can be induced by mechanical stress and may function in one of the most critical defense systems for structural and mechanical fitness.
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