ReviewMolecular interventions2005
Discovery and therapeutic promise of selective androgen receptor modulators.
Review in Molecular interventions, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Exploring Cutting-Edge Strategies for the Management of Triple-Negative Breast Cancer Through Drug Repurposing.Current topics in medicinal chemistry · 2026Review
- Selective Androgen Receptor Modulators: An Emerging Liver Toxin.Journal of clinical and translational hepatology · 2023Review
- A combined treatment with selective androgen and estrogen receptor modulators prevents bone loss in orchiectomized rats.Journal of endocrinological investigation · 2022Article
- Article
- Drug Repurposing for Triple-Negative Breast Cancer.Journal of personalized medicine · 2020Review
- Dietary Supplement and Food Contaminations and Their Implications for Doping Controls.Foods (Basel, Switzerland) · 2020Review
- Neural network activation similarity: a new measure to assist decision making in chemical toxicology.Chemical science · 2020Article
- Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications.Sexual medicine reviews · 2019Review
- Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus.Molecular endocrinology (Baltimore, Md.) · 2015Article
- Evaluation of Resettin® on serum hormone levels in sedentary males.Journal of the International Society of Sports Nutrition · 2014Article
- Nuclear receptors and their selective pharmacologic modulators.Pharmacological reviews · 2013Review
- Alanine aminotransferase regulation by androgens in non-hepatic tissues.Pharmaceutical research · 2012Article
- The androgen receptor and its use in biological assays: looking toward effect-based testing and its applications.Journal of analytical toxicology · 2011Review
- Article
- Sex hormones, their receptors and bone health.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2008Review
- An open label, dose response study to determine the effect of a dietary supplement on dihydrotestosterone, testosterone and estradiol levels in healthy males.Journal of the International Society of Sports Nutrition · 2008Article
- Selective androgen receptor modulators in preclinical and clinical development.Nuclear receptor signaling · 2008Review
- Ligand binding to the androgen receptor induces conformational changes that regulate phosphatase interactions.Molecular and cellular biology · 2007Article
- Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs).Drug discovery today · 2007Review
- Ockham's razor and selective androgen receptor modulators (SARMs): are we overlooking the role of 5alpha-reductase?Molecular interventions · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Androgens are essential for male development and the maintenance of male secondary characteristics, such as bone mass, muscle mass, body composition, and spermatogenesis. The main disadvantages of steroidal androgens are their undesirable physicochemical and pharmacokinetic properties. The recent discovery of nonsteroidal selective androgen receptor modulators (SARMs) provides a promising alternative for testosterone replacement therapies with advantages including oral bioavailability, flexibility of structural modification, androgen receptor specificity, tissue selectivity, and the lack of steroid-related side effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.