ReviewCurrent neurology and neuroscience reports2005
Restless legs syndrome.
Review in Current neurology and neuroscience reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Prevalence of restless legs syndrome in North American and Western European populations: a systematic review.Sleep medicine · 2011Pooled it
- Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multi-center study.Journal of neurology · 2010Trial
- Treatment of Depression with Vortioxetine in a Patient with Comorbid Major Depressive Disorder and Restless Legs Syndrome: A Case Report.Noro psikiyatri arsivi · 2022Article
- Mitochondrial ferritin in the regulation of brain iron homeostasis and neurodegenerative diseases.Frontiers in pharmacology · 2014Review
- Restless legs syndrome in a group of patients with Alzheimer's disease.American journal of Alzheimer's disease and other dementias · 2013Article
- Reduced neural synchrony in patients with restless legs syndrome during a visual oddball task.PloS one · 2012Article
- Sleep problems in children and adolescents with common medical conditions.Pediatric clinics of North America · 2011Review
- Rotigotine transdermal patch: in restless legs syndrome.CNS drugs · 2008Review
- The Prevalence of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Systematic Review and Meta-analysis Study.Basic and clinical neuroscienceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Restless legs syndrome is a very common and still under-diagnosed neurologic condition that can cause severe morbidity. The pathology centers around central nervous system iron homeostatic dysregulation with subsequent alterations in dopaminergic functioning. Genetic studies will hopefully soon identify specific abnormalities. Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.