ArticleAnnals of general psychiatry2005
Depression and Obstructive Sleep Apnea (OSA).
Article in Annals of general psychiatry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 3 syntheses or guidelines pooled it, 271 citations in OpenAlex.
- Prevalence and clinical aspects of obstructive sleep apnea in Parkinson disease: A meta-analysis.European journal of neurology · 2024Pooled it
- Association between obstructive sleep apnea and erectile dysfunction: a systematic review and meta-analysis.International journal of impotence research · 2018Pooled it
- The relationship between depressive symptoms and obstructive sleep apnea in pediatric populations: a meta-analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2013Pooled it
- Obstructive sleep apnea/hypopnea syndrome and poor response to sertraline in patients with coronary heart disease.The Journal of clinical psychiatry · 2012Trial
- Frequency and predictors of obstructive sleep apnea among individuals with major depressive disorder and insomnia.Journal of psychosomatic research · 2009Trial
- Impact of CPAP therapy on geriatric depression scale scores in elderly patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2026Article
- Sleep Quality, Relationship Functioning, and Health-Related Quality of Life in Partners of CPAP-Treated OSA Patients.Clinical psychology in Europe · 2026Article
- Mood Disorders and Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Association between obstructive sleep apnea symptom subtypes and mental health.Respiratory research & clinical practice · 2026Observational
- Article
- Potential diagnostic markers and therapeutic targets for obstructive sleep apnea with comorbid depression based on bioinformatics analysis.Frontiers in genetics · 2025Article
- Prevalence and risk factors of obstructive sleep apnea in depression: an observational retrospective study.Frontiers in psychiatry · 2025Article
- Nocturia and obstructive sleep apnoea.Nature reviews. Urology · 2024Review
- Respiration-triggered olfactory stimulation reduces obstructive sleep apnea severity: A prospective pilot study.Journal of sleep research · 2024Article
- Prevalence and factors associated with high risk for obstructive sleep apnea in schizophrenia spectrum disorder patients on long-term clozapine.Indian journal of psychiatry · 2024Article
- Using the Complex Network Model to Associate Nutritional, Psychological, and Physical Parameters and Aspects of Sleep with Depression Symptoms.Journal of clinical medicine · 2024Article
- Risk of Comorbid Insomnia Disorder Associated with Major Depression in Apneic Patients: A Cross-Sectional Study.Clocks & sleep · 2024Article
- Article
- A Narrative Review of Self-Reported Scales to Evaluate Depression and Anxiety Symptoms in Adult Obstructive Sleep Apnea Patients.Medicina (Kaunas, Lithuania) · 2024Review
- Assessing the causal relationship between psychiatric disorders and obstructive sleep apnea: a bidirectional Mendelian randomization.Frontiers in psychiatry · 2024Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
For over two decades clinical studies have been conducted which suggest the existence of a relationship between depression and Obstructive Sleep Apnea (OSA). Recently, Ohayon underscored the evidence for a link between these two disorders in the general population, showing that 800 out of 100,000 individuals had both, a breathing-related sleep disorder and a major depressive disorder, with up to 20% of the subjects presenting with one of these disorders also having the other. In some populations, depending on age, gender and other demographic and health characteristics, the prevalence of both disorders may be even higher: OSA may affect more than 50% of individuals over the age of 65, and significant depressive symptoms may be present in as many as 26% of a community-dwelling population of older adults. In clinical practice, the presence of depressive symptomatology is often considered in patients with OSA, and may be accounted for and followed-up when considering treatment approaches and response to treatment. On the other hand, sleep problems and specifically OSA are rarely assessed on a regular basis in patients with a depressive disorder. However, OSA might not only be associated with a depressive syndrome, but its presence may also be responsible for failure to respond to appropriate pharmacological treatment. Furthermore, an undiagnosed OSA might be exacerbated by adjunct treatments to antidepressant medications, such as benzodiazepines. Increased awareness of the relationship between depression and OSA might significantly improve diagnostic accuracy as well as treatment outcome for both disorders. In this review, we will summarize important findings in the current literature regarding the association between depression and OSA, and the possible mechanisms by which both disorders interact. Implications for clinical practice will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.