ArticleThe Plant cell2005
A Link between ethylene and auxin uncovered by the characterization of two root-specific ethylene-insensitive mutants in Arabidopsis.
Article in The Plant cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers.
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Who cites it
207 citing papers in PubMed, 473 citations in OpenAlex.
- Duet between sugars and hormones: The molecular dialogue fine-tuning hypoxia acclimation in plants.Journal of integrative plant biology · 2026Review
- EBSn, a Robust Synthetic Reporter for Monitoring Ethylene Responses in Plants.Plant biotechnology journal · 2026Article
- The IAOx-Dependent IAA Biosynthesis Pathway: Acquired Insights, Paradigm Shifts, and Unresolved Questions.Plants (Basel, Switzerland) · 2026Review
- A localized disruption in auxin status leading to root system defects under elevated temperature environments.Plant cell reports · 2025Article
- The CYP71A, NIT, AMI, and IAMH gene families are dispensable for indole-3-acetaldoxime-mediated auxin biosynthesis in Arabidopsis.The Plant cell · 2025Article
- To grow or not to grow: the enigma of plant root growth dynamism.Plant molecular biology · 2025Review
- Exogenous application of the apocarotenoid retinaldehyde negatively regulates auxin-mediated root growth.Plant physiology · 2024Article
- The underground tango: How ethylene and auxin interact to regulate cereal root angle.Plant physiology · 2024Article
- Determination of Bioactive Compound Kynurenic Acid inMolecules (Basel, Switzerland) · 2024Article
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- Ethylene and its crosstalk with hormonal pathways in fruit ripening: mechanisms, modulation, and commercial exploitation.Frontiers in plant science · 2024Review
- Phosphoribosyltransferases and Their Roles in Plant Development and Abiotic Stress Response.International journal of molecular sciences · 2023Review
- The nitrate transporter NRT2.1 directly antagonizes PIN7-mediated auxin transport for root growth adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Comparative Coexpression Analysis of Indole Synthase and Tryptophan Synthase A Reveals the Independent Production of Auxin via the Cytosolic Free Indole.Plants (Basel, Switzerland) · 2023Article
- Auxin contributes to jasmonate-mediated regulation of abscisic acid signaling during seed germination in Arabidopsis.The Plant cell · 2023Article
- Integrative Transcriptome, miRNAs, Degradome, and Phytohormone Analysis ofInternational journal of molecular sciences · 2023Article
- ZmmiR169q/ZmNF-YA8 is a module that homeostatically regulates primary root growth and salt tolerance in maize.Frontiers in plant science · 2023Article
- Ethylene response factor ERF.D7 activates auxin response factor 2 paralogs to regulate tomato fruit ripening.Plant physiology · 2022Article
- The bioactive potential of phytohormones: A review.Biotechnology reports (Amsterdam, Netherlands) · 2022Review
147 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant hormone ethylene participates in the regulation of a variety of developmental processes and serves as a key mediator of plant responses to biotic and abiotic stress factors. The diversity of ethylene functions is achieved, at least in part, by combinatorial interactions with other hormonal signals. Here, we show that ethylene-triggered inhibition of root growth, one of the classical effects of ethylene in Arabidopsis thaliana seedlings, is mediated by the action of the WEAK ETHYLENE INSENSITIVE2/ANTHRANILATE SYNTHASE alpha1 (WEI2/ASA1) and WEI7/ANTHRANILATE SYNTHASE beta1 (ASB1) genes that encode alpha- and beta-subunits of a rate-limiting enzyme of Trp biosynthesis, anthranilate synthase. Upregulation of WEI2/ASA1 and WEI7/ASB1 by ethylene results in the accumulation of auxin in the tip of primary root, whereas loss-of-function mutations in these genes prevent the ethylene-mediated auxin increase. Furthermore, wei2 and wei7 suppress the high-auxin phenotypes of superroot1 (sur1) and sur2, two auxin-overproducing mutants, suggesting that the roles of WEI2 and WEI7 in the regulation of auxin biosynthesis are not restricted to the ethylene response. Together, these findings reveal that ASA1 and ASB1 are key elements in the regulation of auxin production and an unexpected node of interaction between ethylene responses and auxin biosynthesis in Arabidopsis. This study provides a mechanistic explanation for the root-specific ethylene insensitivity of wei2 and wei7, illustrating how interactions between hormones can be used to achieve response specificity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.