Trial reportEuropean journal of applied physiology2005
Changes of motor drive, cortical arousal and perceived exertion following prolonged cycling to exhaustion.
Trial report in European journal of applied physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02014233 (The Effect of Short Term Omega-3 Supplementation on Exercise Performance and Neuromuscular Function.), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Short Term Omega-3 Supplementation on Exercise Performance and Neuromuscular Function.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Effects of internal cooling on physical performance, physiological and perceptional parameters when exercising in the heat: A systematic review with meta-analyses.Frontiers in physiology · 2023Pooled it
- Reliability and suitability of physiological exercise response and recovery markers.Scientific reports · 2020Trial
- Caffeine Affects Time to Exhaustion and Substrate Oxidation during Cycling at Maximal Lactate Steady State.Nutrients · 2015Trial
- Evaluation of the numeric rating scale for perception of effort during isometric elbow flexion exercise.European journal of applied physiology · 2012Trial
- Psychophysiological Responses in Soldiers during Close Combat: Implications for Occupational Health and Fitness in Tactical Populations.Healthcare (Basel, Switzerland) · 2023Article
- Effects of Oral Branched-Chain Amino Acids (BCAAs) Intake on Muscular and Central Fatigue During an Incremental Exercise.Journal of human kinetics · 2020Article
- Conduction Velocity of Muscle Action Potential of Knee Extensor Muscle During Evoked and Voluntary Contractions After Exhaustive Leg Pedaling Exercise.Frontiers in physiology · 2020Article
- The effect of fatigue and duration knowledge of exercise on kicking performance in soccer players.Journal of sport and health science · 2019Article
- Evaluation of Central Fatigue by the Critical Flicker Fusion Threshold in Cyclists.Journal of medical systems · 2019Article
- Cortical neural arousal is differentially affected by type of physical exercise performed.Experimental brain research · 2018Article
- Use of Biotechnological Devices in the Quantification of Psychophysiological Workload of Professional Chess Players.Journal of medical systems · 2018Article
- Central activation, metabolites, and calcium handling during fatigue with repeated maximal isometric contractions in human muscle.European journal of applied physiology · 2017Article
- Use of Biotechnology Devices to Analyse Fatigue Process in Swimming Training.Journal of medical systems · 2017Article
- Effects of physical exercise on individual resting state EEG alpha peak frequency.Neural plasticity · 2015Article
- Interactive processes link the multiple symptoms of fatigue in sport competition.Sports medicine (Auckland, N.Z.) · 2011Review
- Do multiple ionic interactions contribute to skeletal muscle fatigue?The Journal of physiology · 2008Review
- Is peripheral locomotor muscle fatigue during endurance exercise a variable carefully regulated by a negative feedback system?The Journal of physiology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims of this study were to (1) quantify any central fatigue that occurs following prolonged dynamic exercise, i.e. reduced muscle force caused by impaired motor drive from the central nervous system and (2) determine whether decreased cortical arousal, assessed using critical flicker fusion threshold (CFF), occurs and is related to impaired exercise performance. Fifteen healthy men cycled at 70% VO2peak until exhaustion. The peak force of maximum voluntary isometric contractions (MVC) of the quadriceps muscle group was reduced by 30% at exhaustion. The voluntary activation ratio determined using superimposed tetanic stimulation fell from 0.99 to 0.86 at exhaustion. The central fatigue (%) at exhaustion was 33+/-12% (+/- SD) (assessed via the tetanus interpolation technique) and 54+/-32% (assessed via the relative decline of MVC and peak tetanic force) of the total fatigue. The MVC only partially recovered and central fatigue persisted at 30 min post-exercise. CFF increased from 39.2+/-2.3 to 41.8+/-3.5 Hz at exhaustion, but did not correlate with central fatigue. Every subject reached the highest rating of perceived exertion (RPE) at exhaustion of 20 on the Borg scale. The time to exhaustion was related to how quickly the RPE increased and to the ability to sustain exercise at very high RPE. These data suggest that with prolonged cycling: (1) there is considerable and a persistent form of central fatigue, (2) there is an increased level of cortical arousal, and (3) exhaustion is linked to very high subjective RPE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.