Evidence map›Paper›PMID 15973521›Full record

ArticleIntensive care medicine2005

Inhaled nitric oxide therapy in adults: European expert recommendations.

Peter Germann, Antonio Braschi, Giorgio Della Rocca, Anh Tuan Dinh-Xuan, Konrad Falke, Claes Frostell, Lars E Gustafsson, Philippe Hervé, Philippe Jolliet, Udo Kaisers and 10 more

Registry-linked trialOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04988932 (Inhalative Stickstoffmonoxid), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04988932 nacompletednot on this mapstarted 2012, after this paper: background citation

Inhalative Stickstoffmonoxid (NO) Behandlung Bei Patienten Mit Schwerem, therapierefraktärem Zerebralen Vasospasmus Nach Subarachnoidalblutung

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2012 to 2020Enrolled7ConditionsSAH, Inhaled Nitric Oxide, Cerebral Ischemia, VasospasmArmsInhaled nitric oxide
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.

  1. Inhaled Nitric Oxide for Clinical Management of COVID-19: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  2. Trial
  3. Successful management of severeFrontiers in medicine · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 10 countries.

Peter GermannDepartment of Anaesthesiology and General Intensive Care, Medical University of Vienna, Waehringerguertel 18-20, 1090 Vienna, Austria. peter.germann@meduniwien.ac.at
Antonio Braschi
Giorgio Della Rocca
Anh Tuan Dinh-Xuan
Konrad Falke
Claes Frostell
Lars E Gustafsson
Philippe Hervé
Philippe Jolliet
Udo Kaisers
Hector Litvan
Duncan J Macrae
Marco Maggiorini
Nandor Marczin
Bernd Mueller
Didier Payen
Marco Ranucci
Dietmar Schranz
Rainer Zimmermann
Roman Ullrich
Medical University of Vienna · ATCentre Chirurgical Marie Lannelongue · FRCharité - Universitätsmedizin Berlin · DEGlanrhyd Hospital · GBHarefield Hospital · GBHôpital Cochin · FRHôpital Lariboisière · FRHospital de Sant Pau · ESIRCCS Policlinico San Donato · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITKarolinska Institutet · SERoyal Brompton Hospital · GBUniversidad CES · COUniversity Hospital of Geneva · CHUniversity Medical Center · USUniversity of Udine · ITUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInhaled nitric oxide (iNO) has been used for treatment of acute respiratory failure and pulmonary hypertension since 1991 in adult patients in the perioperative setting and in critical care.

methodsThis contribution assesses evidence for the use of iNO in this population as presented to a expert group jointly organised by the European Society of Intensive Care Medicine and the European Association of Cardiothoracic Anaesthesiologists.

conclusionsExpert recommendations on the use of iNO in adults were agreed on following presentation of the evidence at the expert meeting held in June 2004.

Indexed as

Administration, InhalationAdultEuropeHeart FailureHumansHypertension, PulmonaryNitric OxidePractice Guidelines as TopicReperfusion InjuryRespiratory Distress SyndromeRespiratory TherapyNitric Oxide

Identifiers

PMID15973521
OpenAlexW2038535913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.