Evidence map›Paper›PMID 15973100›Full record

ArticleAnnals of surgery2005

Restoration of normal distensive characteristics of the esophagogastric junction after fundoplication.

John E Pandolfino, Jennifer Curry, Guoxiang Shi, Raymond J Joehl, James G Brasseur, Peter J Kahrilas

Open access · greenAbstract readComparative Study
In one paragraph

Article in Annals of surgery, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 69 citations in OpenAlex.

  1. Trial
  2. Length and pressure of the reconstructed lower esophageal sphincter is determined by both crural closure and Nissen fundoplication.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013
    Trial
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  15. Electrical stimulation therapy for gastroesophageal reflux disease.Journal of neurogastroenterology and motility · 2014
    Article
  16. Esophageal motility abnormalities in gastroesophageal reflux disease.World journal of gastrointestinal pharmacology and therapeutics · 2014
    Review
  17. Article
  18. Article
  19. Article
  20. Esophagogastric junction distensibility after fundoplication assessed with a novel functional luminal imaging probe.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2010
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John E PandolfinoDepartment of Medicine, Northwestern University Medical School, Chicago, IL, USA.
Jennifer Curry
Guoxiang Shi
Raymond J Joehl
James G Brasseur
Peter J Kahrilas
Northwestern University · US

Funding

Anatomic and Mechanical Variables of the EGJ in GERDK23DK062170 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2002 to 2006
$557k
VOLITIONAL, BOLUS, AND AGE EFFECTS ON SWALLOWINGR01DC000646 · NIDCD · NORTHWESTERN UNIVERSITY · PI KAHRILAS, PETER J. · 1990 to 2000
$188k
NIDCD NIH HHS R01 DC00646NIDDK NIH HHS K23 DK062170NIDDK NIH HHS K23 DK062170-01
6 · The paper itself

Abstract

objectiveTo study the mechanical characteristics of the esophagogastric junction (EGJ) of postfundoplication patients and compare them with previously reported data on normal subjects and GERD patients.

methodsEight normal subjects, 9 GERD patients, and 8 fundoplication patients were studied with concurrent manometry, fluoroscopy, and stepwise controlled barostat distention of the EGJ. The minimal barostat pressure required to open the EGJ during the interswallow period was determined. Thereafter, barium swallows were imaged in 5-mm Hg increments of intrabag pressure. EGJ diameter and length were measured at each pressure during deglutitive relaxation.

resultsEGJ opening diameter during deglutitive relaxation was on average 0.5 cm greater in GERD patients compared with normal subjects and fundoplication patients (P < 0.05). EGJ opening pressure and opening diameter were comparable between normal subjects and fundoplication patients; however, the EGJ length was 32% longer in fundoplication patients.

conclusionsFundoplication restores distensibility of the EGJ to a level similar to normal subjects. Since trans-EGJ flow is related to EGJ length and EGJ diameter, these findings suggest that retrograde flow through the EGJ would be decreased by both a reduction in diameter and an increase in length of the EGJ.

Indexed as

AdultAgedCase-Control StudiesEndoscopy, GastrointestinalEsophagogastric JunctionFemaleFollow-Up StudiesFundoplicationGastroesophageal RefluxHernia, HiatalHumansMaleManometryMiddle AgedPostoperative ComplicationsRecovery of Function

Identifiers

PMID15973100
PMCPMC1357703
OpenAlexW2165166315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.