ArticleInfection and immunity2005
Effects of a probiotic strain of Enterococcus faecium on the rate of natural chlamydia infection in swine.
Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 108 citations in OpenAlex.
- Feeding of the probiotic bacterium Enterococcus faecium NCIMB 10415 differentially affects shedding of enteric viruses in pigs.Veterinary research · 2012Trial
- Influence of the probiotic Bacillus cereus var. toyoi on the intestinal immunity of piglets.Veterinary immunology and immunopathology · 2007Trial
- Effects of Supplemental Effective Microorganisms in Feed on the Growth, Lipid Deposition and GH-IGF-I Axis of the Blunt Snout BreamAquaculture nutrition · 2026Article
- Zinc Oxide Administration Relieves the Diarrhea of ETEC K88-Infected Piglets by Reducing Ileal Apoptosis and Maintaining Gut Microbial Balance.Veterinary sciences · 2025Article
- Use of Microorganisms as Nutritional and Functional Feedstuffs for Nursery Pigs and Broilers.Animals : an open access journal from MDPI · 2022Review
- Enterocins: Classification, Synthesis, Antibacterial Mechanisms and Food Applications.Molecules (Basel, Switzerland) · 2022Review
- Probiotics: Symbiotic Relationship with the Animal Host.Animals : an open access journal from MDPI · 2022Review
- Whole genome sequence analyses-based assessment of virulence potential and antimicrobial susceptibilities and resistance of Enterococcus faecium strains isolated from commercial swine and cattle probiotic products.Journal of animal science · 2022Article
- Probiotic potential and safety assessment of bacteriocinogenicCurrent research in microbial sciences · 2021Article
- Article
- Different Responses of Microbiota across Intestinal Tract toMicroorganisms · 2021Article
- The use of probiotics in animal feeding for safe production and as potential alternatives to antibiotics.Veterinary world · 2021Review
- Peptide ELISA and FRET-qPCR Identified a Significantly Higher Prevalence ofPathogens (Basel, Switzerland) · 2020Article
- Evaluation of safety and probiotic properties of a strain ofJournal of food science and technology · 2020Article
- Pretreatment with probiotic Enterococcus faecium NCIMB 11181 ameliorates necrotic enteritis-induced intestinal barrier injury in broiler chickens.Scientific reports · 2019Article
- Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro- and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a Culture of Polymorphonuclear Cells Isolated from Colostrum.Probiotics and antimicrobial proteins · 2019Article
- Article
- Effects of Dietary Supplementation WithFrontiers in veterinary science · 2019Article
- Anti-TGEV Miller Strain Infection Effect ofFrontiers in microbiology · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chlamydiae are obligately intracellular pathogens which cause infections associated with a broad range of diseases in both livestock and humans. In addition, a large proportion of animals may become persistently infected asymptomatic carriers and serve as reservoirs for other animals which also shed these potential zoonotic pathogens. Reducing the chlamydial load of animals is therefore of major importance, and since large-scale antibiotic treatment is neither desired nor feasible, alternative means of prevention are needed. Here we performed a study comparing the efficacy of a probiotic strain of Enterococcus faecium on the reduction of both the rate of natural infection and the shedding of chlamydiae in swine. The presence of Chlamydiaceae was detected by species-specific PCR of fecal samples of sows taken at three times prior to the birth of piglets. Piglets delivered from chlamydia-positive sows in either the control or the probiotic group were also examined for the frequency of chlamydiae at various ages. Eighty-five percent of the piglets from the control group were found to be chlamydia positive, whereas chlamydiae were found in only 60% of piglets from the probiotic group, results confirmed by fluorescence in situ hybridization and immunohistology, which showed higher rates of infection in the control group. In addition to the reduced frequency of chlamydia-positive piglets in the probiotic group, the time of appearance of positive samples was delayed. To our knowledge, these data show for the first time that a probiotic strain of E. faecium can reduce the rate of carryover infections of piglets by obligate intracellular pathogens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.