Evidence map›Paper›PMID 15971505›Full record

ArticleEuropean journal of epidemiology2005

Smoking as a determinant for plasma levels of testosterone, androstenedione, and DHEAs in postmenopausal women.

Jonas Manjer, Robert Johansson, Per Lenner

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Article in European journal of epidemiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  5. Article
  6. Smoking Across the Menopausal Transition in a 10-Year Longitudinal Sample: The Role of Sex Hormones and Depressive Symptoms.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonas ManjerThe Malmö Diet and Cancer Study, Department of Community Medicine, Malmö University Hospital, Malmö. jonas.manjer@smi.mas.lu.se
Robert Johansson
Per Lenner

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to investigate whether current smoking, ex-smoking, or amount of current smoking among postmenopausal women was associated with plasma levels of testosterone, and rostenedione, and DHEAs. About 65,000 women in Sweden have participated in two population-based prospective cohort studies where blood samples were collected at baseline, and information on life-style, reproductive history and anthropometrical measurements were available. The present study was based on 407 control subjects from a previous nested case-control study on the relation between steroid hormone levels and risk of breast cancer. A multivariate logistic regression analysis, adjusted for potential confounders, was used in order to obtain odds ratios (OR) with 95% confidence intervals. There was a high risk of high testosterone levels (above the median) in current vs. never smokers, OR: 1.85 (1.06-3.23). Risk of high testosterone levels increased by amount of daily smoking (increments of 10 cigarettes/day), OR: 1.55 (1.02-2.37). Ex-smoking was associated with high testosterone levels, OR: 1.56 (0.98-2.47). Current smoking and increasing amount of current smoking were weakly associated with high androstenedione levels. However, these associations did not reach statistical significance. No association was seen between smoking habits and DHEAs levels. We conclude that current smoking, and increasing amount of daily smoking, is associated with high testosterone levels.

Indexed as

PostmenopauseAgedAndrostenedioneCase-Control StudiesCohort StudiesDehydroepiandrosteroneFemaleHumansMaleMiddle AgedOdds RatioSmokingTestosteroneAndrostenedioneDehydroepiandrosteroneTestosterone

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.