Evidence map›Paper›PMID 15970068›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2005

The prescribing of methadone and other opioids to addicts: national survey of GPs in England and Wales.

John Strang, Janie Sheridan, Claire Hunt, Bethanne Kerr, Clare Gerada, Michael Pringle

Abstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Can antiviral treatment for hepatitis C be safely and effectively delivered in primary care?: a narrative systematic review of the evidence base.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
    Pooled it
  3. Comparison of methadone and buprenorphine for opiate detoxification (LEEDS trial): a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011
    Pooled it
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  9. Opiate addiction and overdose: experiences, attitudes, and appetite for community naloxone provision.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017
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  18. A 5-year evaluation of a methadone medical maintenance program.Journal of substance abuse treatment · 2006
    Article
  19. Methadone tolerance testing in drug misusers.BMJ (Clinical research ed.) · 2006
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

John StrangNational Addiction Centre (NAC), Institute of Psychiatry, King's College London & The Maudsley. j.strang@iop.kcl.ac.uk
Janie Sheridan
Claire Hunt
Bethanne Kerr
Clare Gerada
Michael Pringle

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGPs occupy a pivotal position in relation to providing services to opiate misusers in the UK, and this is now cited to support initiatives in other countries.

aimsTo investigate GP involvement in the management of opiate misusers; and to examine the nature of this prescribing of methadone and other opioids.

designGP data collected via self-completion postal questionnaire from a 10% random sample of the 30 000 GPs across England and Wales. Patient prescription data obtained on opiate misusers treated during the preceding 4 weeks.

settingPrimary healthcare practice in England and Wales in mid-2001.

methodA questionnaire was mailed to a random 10% sample of GPs stratified by number of partners in the practice, with three follow-up mailshots. Data on drugs prescribed by these practitioners were also studied, including drug prescribed, form, dose and dispensing arrangements.

resultsThe response rate was 66%. Opiate misusers had been seen by 51% of GPs in the preceding 4 weeks (mean of 4.1 such patients), of whom 50% had prescribed opiate-substitution drugs. This provided a study sample of 1482 opiate misusers to whom GPs were prescribing methadone (86.7%), dihydrocodeine (8.5%) or buprenorphine (4.4%). Of 1292 methadone prescriptions, mean daily dose was 36.9 mg - 47.9% being for 30 mg or less. Daily interval dispensing was stipulated by 44.6%, while 42.9% permitted weekly take-away supply.

conclusionsIn 2001 nearly three times as many GPs were seeing opiate misusers than was the case in 1985. Half were prescribing substitute-opiate drugs such as methadone (to an estimated 30 000 patients). However, there are grounds for concern about the quality of this prescribing. Most doses were too low to constitute optimal methadone maintenance; widespread disregard of the availability of supervised or interval dispensing increases the risks of diversion to the blackmarket and deaths from methadone overdose. Increased quantity of care has been achieved. Increased quality is now required.

Indexed as

Analgesics, OpioidBuprenorphineCodeineCohort StudiesEnglandFamily PracticeFemaleHumansMaleMethadoneNarcoticsOpioid-Related DisordersOrganizational PolicyPractice Patterns, Physicians'WalesAnalgesics, OpioidBuprenorphineCodeinedihydrocodeineMethadoneNarcotics

Identifiers

PMID15970068
PMCPMC1472740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.