ArticleJournal of bacteriology2005
Host- and tissue-specific pathogenic traits of Staphylococcus aureus.
Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 104 citations in OpenAlex.
- Key role for clumping factor B in Staphylococcus aureus nasal colonization of humans.PLoS medicine · 2008Trial
- MRSA Profiles Reveal Age- and Gender-Specificity in a Tertiary Care Hospital: High Burden in ICU Elderly and Emerging Community Patterns in Youth.Microorganisms · 2025Article
- Identification of the Enterotoxigenic Potential ofToxins · 2023Article
- Community-Acquired Methicillin-ResistantDiagnostics (Basel, Switzerland) · 2023Article
- Molecular and Source-Specific Profiling of HospitalMicroorganisms · 2023Article
- Article
- Virulence Factors and Phylogeny ofFrontiers in veterinary science · 2020Article
- Characterization of Staphylococcus aureus isolated from milk samples of dairy cows in small holder farms of North-Western Ethiopia.BMC veterinary research · 2018Article
- Isoenzymatic genotyping of Staphylococcus aureus from dairy cattle and human clinical environments reveal evolutionary divergences.Revista do Instituto de Medicina Tropical de Sao Paulo · 2018Article
- Article
- Prevalence of Subclinical Mastitis and Distribution of Pathogens in Dairy Farms of Rubavu and Nyabihu Districts, Rwanda.Journal of veterinary medicine · 2017Article
- Recombination-mediated remodelling of host-pathogen interactions duringMicrobial genomics · 2015Article
- Staphylococcal enterotoxin H induced apoptosis of bovine mammary epithelial cells in vitro.Toxins · 2014Article
- Staphylococcus aureus from 152 cases of bovine, ovine and caprine mastitis investigated by Multiple-locus variable number of tandem repeat analysis (MLVA).Veterinary research · 2014Article
- Detection of the enterotoxigenic genes (Comparative clinical pathology · 2013Article
- Molecular analysis of human and canine Staphylococcus aureus strains reveals distinct extended-host-spectrum genotypes independent of their methicillin resistance.Applied and environmental microbiology · 2013Article
- Use of 5-Enolpyruvylshikmate-3-Phosphate Synthase Encoding Gene for Typing of Staphylococcus aureus Isolated from Skin and Urinary Tract Infections of Human.Iranian journal of basic medical sciences · 2012Article
- HLA molecules and nasal carriage of Staphylococcus aureus isolated from dialysis and kidney transplant patients at a hospital in Southern Brazil.BMC research notes · 2012Article
- Comparative host specificity of human- and pig- associated Staphylococcus aureus clonal lineages.PloS one · 2012Article
- Mastitis: comparative etiology and epidemiology.Journal of mammary gland biology and neoplasia · 2011Review
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comparative genomics were used to assess genetic differences between Staphylococcus aureus strains derived from infected animals versus colonized or infected humans. A total of 77 veterinary isolates were genetically characterized by high-throughput amplified fragment length polymorphism (AFLP). Bacterial genotypes were introduced in a large AFLP database containing similar information for 1,056 human S. aureus strains. All S. aureus strains isolated from animals in close contact with humans (e.g., pet animals) were predominantly classified in one of the five main clusters of the AFLP database (cluster I). In essence, mastitis-associated strains from animals were categorized separately (cluster IVa) and cosegregated with bacteremia-associated strains from humans. Distribution of only 2 out of 10 different virulence genes differed across the clusters. The gene encoding the toxic shock syndrome protein (tst) was more often encountered among veterinary strains (P < 0.0001) and even more in the mastitis-related strains (P<0.0001) compared to human isolate results. The gene encoding the collagen binding protein (cna) was rarely detected among invasive human strains. The virulence potential, as indicated by the number of virulence genes per strain, did not differ significantly between the human- and animal-related strains. Our data show that invasive infections in pets and humans are usually due to S. aureus strains with the same genetic background. Mastitis-associated S. aureus isolated in diverse farm animal species form a distinct genetic cluster, characterized by an overrepresentation of the toxic shock syndrome toxin superantigen-encoding gene.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.