ArticleThe Journal of experimental medicine2005
Nonhuman primate models of asthma.
Article in The Journal of experimental medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 63 citations in OpenAlex.
- Review
- A Novel Nonhuman Primate Model of Nonatopic Asthma.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Targeting the OXE receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates.British journal of pharmacology · 2022Article
- G Protein-Coupled Receptors in Asthma Therapy: Pharmacology and Drug Action.Pharmacological reviews · 2020Review
- Asthma in an Adult Female Vervet Monkey (Chlorocebus sabaeus).Comparative medicine · 2016Article
- Identifying rhesus macaque gene orthologs using heterospecific human CNV probes.Genomics data · 2015Article
- Dynamics of IL-4 and IL-13 expression in the airways of sheep following allergen challenge.BMC pulmonary medicine · 2015Article
- Heterospecific SNP diversity in humans and rhesus macaque (Macaca mulatta).Journal of medical primatology · 2015Article
- A novel nonhuman primate model of cigarette smoke-induced airway disease.The American journal of pathology · 2015Article
- Why primate models matter.American journal of primatology · 2014Review
- Airway hyper-responsiveness in lipopolysaccharide-challenged common marmosets (Callithrix jacchus).Clinical science (London, England : 1979) · 2014Article
- Article
- LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing.PloS one · 2012Article
- Increased mast cell density and airway responses to allergic and non-allergic stimuli in a sheep model of chronic asthma.PloS one · 2012Article
- Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model.The American journal of pathology · 2011Article
- Behavioral inhibition is associated with airway hyperresponsiveness but not atopy in a monkey model of asthma.Psychosomatic medicine · 2011Article
- Functional invariant NKT cells in pig lungs regulate the airway hyperreactivity: a potential animal model.Journal of clinical immunology · 2011Article
- Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates.Journal of asthma and allergy · 2010Article
- Direct activation of natural killer T cells induces airway hyperreactivity in nonhuman primates.The Journal of allergy and clinical immunology · 2008Article
- A review of antisense therapeutic interventions for molecular biological targets in asthma.Biologics : targets & therapy · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a complex human disease that does not have an accurate counterpart in any common model organism. Most of our understanding of the immune mechanisms underlying asthma comes from studies in man and mouse. However, there are fundamental differences between the spontaneous disease in man and the experimentally induced counterparts in mice. We advocate more extensive use of nonhuman primate asthma models to reconcile these differences between man and mouse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.