Evidence map›Paper›PMID 15967127›Full record

ArticleMolecular imaging

An interventional magnetic resonance imaging technique for the molecular characterization of intraprostatic dynamic contrast enhancement.

Cynthia Ménard, Robert C Susil, Peter Choyke, Jonathan Coleman, Robert Grubb, Ahmed Gharib, Axel Krieger, Peter Guion, David Thomasson, Karen Ullman and 9 more

Abstract read
In one paragraph

Article in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Development and Evaluation of an Actuated MRI-Compatible Robotic System for MRI-Guided Prostate Intervention.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2012
    Article
  2. Article
  3. Review
  4. Review
  5. Clinical biomarkers of angiogenesis inhibition.Cancer metastasis reviews · 2008
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Cynthia MénardNational Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.
Robert C Susil
Peter Choyke
Jonathan Coleman
Robert Grubb
Ahmed Gharib
Axel Krieger
Peter Guion
David Thomasson
Karen Ullman
Sandeep Gupta
Virginia Espina
Lance Liotta
Emanuel Petricoin
Gabor Fitchtinger
Louis L Whitcomb
Ergin Atalar
C Norman Coleman
Kevin Camphausen

Funding

Transrectal Prostate Therapy Robot in Closed MRI ScannerR01EB002963 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI WHITCOMB, LOUIS LITCHFIELD · 2003 to 2007
$2.0M
Angiogenesis imagingZ01BC010714 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHOYKE, PETER L · 2006 to 2008
$850k
NIBIB NIH HHS R01 EB 002963NIBIB NIH HHS R01 EB002963
6 · The paper itself

Abstract

The biological characterization of an individual patient's tumor by noninvasive imaging will have an important role in cancer care and clinical research if the molecular processes that underlie the image data are known. Spatial heterogeneity in the dynamics of magnetic resonance imaging contrast enhancement (DCE-MRI) is hypothesized to reflect variations in tumor angiogenesis. Here we demonstrate the feasibility of precisely colocalizing DCE-MRI data with the genomic and proteomic profiles of underlying biopsy tissue using a novel MRI-guided biopsy technique in a patients with prostate cancer.

Indexed as

BiopsyContrast MediaHumansImage EnhancementMagnetic Resonance ImagingMaleProstatic NeoplasmsRNA, NeoplasmContrast MediaRNA, Neoplasm

Identifiers

PMID15967127
PMCPMC3299492

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.