Evidence map›Paper›PMID 15966106›Full record

ReviewCellular and molecular neurobiology2005

In vitro methods in the study of viral and prion permeability across the blood-brain barrier.

Ryota Nakaoke, William A Banks

Abstract readReview
In one paragraph

Review in Cellular and molecular neurobiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ryota NakaokeDepartment of Pharmacology 1, Nagasaki University School of Medicine, Nagasaki, Japan.
William A Banks

Funding

Mechanisms of HIV Transport Across the BBBR01NS041863 · NINDS · SAINT LOUIS UNIVERSITY · PI BANKS, WILLIAM A · 2000 to 2004
$1.4M
PTS1 Regulation of Brain Met Enk Levels in AlcoholismR01AA012743 · NIAAA · SAINT LOUIS UNIVERSITY · PI BANKS, WILLIAM A · 2001 to 2004
$966k
NIAAA NIH HHS R01AA12743NINDS NIH HHS R01NS41863
6 · The paper itself

Abstract

(1) Infectious agents capable of entering the central nervous system (CNS) produce some of the most dreaded diseases known to man. The infectious agent within the CNS is often protected by the blood-brain barrier (BBB), shielded from endogenous and exogenous anti-infectious agents. (2) The use of in vitro methods offers many advantages to the study of how infectious agents interact with the BBB. Two such agents which negotiate the BBB early in the course of disease before damage to the BBB are the autoimmune deficiency syndrome virus, or human immunodeficiency virus 1, and scrapie prion. Our laboratories have used in vitro methods to study these agents. (3) Here, we review some of the results form our laboratories and those of others.

Indexed as

HIV-1AIDS Dementia ComplexAnimalsBlood-Brain BarrierHumansIn Vitro TechniquesPrion Diseases

Identifiers

PMID15966106
PMCPMC11529555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.