ArticlePlant physiology2005
Phytic acid synthesis and vacuolar accumulation in suspension-cultured cells of Catharanthus roseus induced by high concentration of inorganic phosphate and cations.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 60 citations in OpenAlex.
- The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA.Nature communications · 2026Article
- Two-sided effects of the organic phosphorus phytate on a globally important marine coccolithophorid phytoplankton.Microbiology spectrum · 2023Article
- Analysis of weighted co-regulatory networks in maize provides insights into new genes and regulatory mechanisms related to inositol phosphate metabolism.BMC genomics · 2016Article
- Horizontal transfer of bacterial polyphosphate kinases to eukaryotes: implications for the ice age and land colonisation.BMC research notes · 2013Article
- Phytic acid and raffinose series oligosaccharides metabolism in developing chickpea seeds.Physiology and molecular biology of plants : an international journal of functional plant biology · 2011Article
- Identification of genes necessary for wild-type levels of seed phytic acid in Arabidopsis thaliana using a reverse genetics approach.Molecular genetics and genomics : MGG · 2011Article
- Article
- The Arabidopsis ATP-binding cassette protein AtMRP5/AtABCC5 is a high affinity inositol hexakisphosphate transporter involved in guard cell signaling and phytate storage.The Journal of biological chemistry · 2009Article
- Isolation and characterization of a low phytic acid rice mutant reveals a mutation in the rice orthologue of maize MIK.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2008Article
- The rice OsLpa1 gene encodes a novel protein involved in phytic acid metabolism.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2008Article
- An Arabidopsis purple acid phosphatase with phytase activity increases foliar ascorbate.Plant physiology · 2008Article
- Localization of myo-inositol-1-phosphate synthase to the endosperm in developing seeds of Arabidopsis.Journal of experimental botany · 2008Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have established a new system for studying phytic acid, myo-inositol hexakisphosphate (InsP(6)) synthesis in suspension-cultured cells of Catharanthus. InsP(6) and other intermediates of myo-inositol (Ins) phosphate metabolism were measured using an ion chromatography method. The detection limit for InsP(6) was less than 50 nM, which was sufficient to analyze Ins phosphates in living cells. Synthesis of Ins phosphates was induced by incubation in high inorganic phosphate medium. InsP(6) was mainly accumulated in vacuoles and was enhanced when cells were grown in high concentration of inorganic phosphates with the cations K(+), Ca(2+), or Zn(2+). However, there was a strong tendency for InsP(6) to accumulate in the vacuole in the presence of Ca(2+) and in nonvacuolar compartments when supplied with Zn(2+), possibly due to precipitation of InsP(6) with Zn(2+) in the cytosol. A vesicle transport inhibitor, brefeldin A, stimulated InsP(6) accumulation. The amounts of both Ins(3)P(1) myo-inositol monophosphate synthase, a key enzyme for InsP(6) synthesis, and Ins(1,4,5)P(3) kinase were unrelated to the level of accumulation of InsP(6). The mechanisms for InsP(6) synthesis and localization into vacuoles in plant cells are discussed.
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