ArticleOccupational and environmental medicine2005
Mortality in the UK industrial silica sand industry: 2. A retrospective cohort study.
Article in Occupational and environmental medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The association between occupational silica exposure and leukemia: a systematic review and meta-analysis of cohort studies.BMC public health · 2025Pooled it
- Occupational exposure to silica and risk of gastrointestinal cancers: a systematic review and meta-analysis of cohort studies.International archives of occupational and environmental health · 2024Pooled it
- Occupational exposure to respirable crystalline silica and lung cancer: a systematic review of cut-off points.Environmental health : a global access science source · 2023Pooled it
- Occupational exposure to respirable crystalline silica and chronic non-malignant renal disease: systematic review and meta-analysis.International archives of occupational and environmental health · 2017Pooled it
- A toxicological profile of silica nanoparticles.Toxicology research · 2022Review
- Article
- Temporal trends in respirable dust and respirable quartz concentrations within the European industrial minerals sector over a 15-year period (2002-2016).Occupational and environmental medicine · 2020Article
- Silica and asbestos exposure at work and the risk of bladder cancer in Canadian men: a population-based case-control study.BMC cancer · 2020Article
- Late age (85 years or older) peak incidence of bladder cancer.The Journal of urology · 2008Article
- Mortality from non-malignant respiratory diseases among people with silicosis in Hong Kong: exposure-response analyses for exposure to silica dust.Occupational and environmental medicine · 2007Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo evaluate the mortality experience of a cohort of employees in the UK silica sand industry exposed to respirable crystalline silica (RCS).
methodsA retrospective cohort mortality study followed all workers to 2001 with at least one year's employment at one of seven UK silica sand producing quarries between 1950 and 1986. Each worker was assigned a job category and cumulative exposure to RCS was estimated using a job-exposure matrix.
resultsA total of 764 deaths were identified in 2703 cohort members. The overall mortality rate for the cohort was lower than would be expected in the general population. Mortality from circulatory and respiratory disease was also less than expected, but death due to pneumoconiosis was slightly raised (two deaths). Mortality from all cancers was slightly decreased. Mortality was not raised in any job category. Cancer mortality was raised at one quarry due to a significant increase in lung (standardised mortality rate (SMR) 162.0, 95% CI 113.5 to 224.3) and bladder (SMR 366.5, 95% CI 167.6 to 695.7) cancers. Mortality from lung cancer and other causes did not show a trend with cumulative exposure to RCS.
conclusionsThis study did not show any consistent relation between RCS exposure (in the absence of other known carcinogens) and the development of lung cancer. This contrasts with a number of studies that have shown positive findings in similar and related industries.
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