ArticleOecologia2005
Cell-mediated immunosenescence in birds.
Article in Oecologia, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 74 citations in OpenAlex.
- Aging-associated dysregulation of homeostatic immune response termination (and not initiation).Aging cell · 2017Article
- Fine-scale spatial age segregation in the limited foraging area of an inshore seabird species, the little penguin.Oecologia · 2014Article
- Extrinsic- and intrinsic-dependent variation in component communities and patterns of aggregations in helminth parasites of great cormorant (Phalacrocorax carbo) from N.E. Poland.Parasitology research · 2014Article
- Article
- Growing old with the immune system: a study of immunosenescence in the zebra finch (Taeniopygia guttata).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2011Article
- Effects of environmental change on wildlife health.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2009Review
- Ageing in a variable habitat: environmental stress affects senescence in parasite resistance in St Kilda Soay sheep.Proceedings. Biological sciences · 2009Article
- Testosterone-mediated trade-offs in the old age: a new approach to the immunocompetence handicap and carotenoid-based sexual signalling.Proceedings. Biological sciences · 2009Article
- Immunosenescence in some but not all immune components in a free-living vertebrate, the tree swallow.Proceedings. Biological sciences · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
The phytohaemagglutinin (PHA) skin test response, used to assess cell-mediated immunity, is known to vary with many social and energetic factors, but the effects of age have received little attention. We found that the PHA response of immature birds was lower than those of the youngest breeding adults and were decreased in adults. Whenever possible, age should be included as a covariate when the PHA skin test is used to assess immunocompetence in ecological immunology. The rate of decline in PHA response differed between species and was inversely correlated with survival. The decrease in the PHA response averaged 57% over an average 80% of the maximum life span, but the absolute rate varied with species lifespan such that the short-lived species showed a greater loss per year than the long-lived species. This link between declining immune function and survival may reflect differences in resource partitioning between species, and suggests that selection may act on investment in immune function to influence maximum life span.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.