Trial reportEuropean journal of applied physiology2005
Inverse relationship between exercise economy and oxidative capacity in muscle.
Trial report in European journal of applied physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- Inverse relationship between changes of maximal aerobic capacity and changes in walking economy after weight loss.European journal of applied physiology · 2018Trial
- Modeling lactate threshold in cycling-influence of sex, maximal oxygen uptake, and cost of cycling in young athletes.European journal of applied physiology · 2025Article
- Timing is everything: the age-related impact of plyometric training on lower limb explosive strength in male adolescents and its general effectiveness in female adolescents.European journal of applied physiology · 2025Article
- Article
- Five Weeks of Aquatic-Calisthenic High Intensity Interval Training Improves Cardiorespiratory Fitness and Body Composition in Sedentary Young Adults.Journal of sports science & medicine · 2020Article
- A Comparison of V̇OInternational journal of exercise science · 2020Article
- Relationship between V̇oJournal of applied physiology (Bethesda, Md. : 1985) · 2019Article
- Combined Aerobic and Resistance Training Increases Stretch- Shortening Cycle Potentiation and Walking Economy in Postmenopausal Women.Frontiers in physiology · 2019Article
- A Rapidly-Incremented Tethered-Swimming test for Defining Domain-Specific Training Zones.Journal of human kinetics · 2017Article
- Impact of age on exercise-induced ATP supply during supramaximal plantar flexion in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2015Article
- Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue.Physiological reports · 2015Article
- Cardiorespiratory Adaptations during Concurrent Aerobic and Strength Training in Men and Women.PloS one · 2015Article
- Influence of individual energy cost on running capacity in warm, humid environments.European journal of applied physiology · 2013Article
- Integrating muscle cell biochemistry and whole-body physiology in humans:(31)P-MRS data from the InSight trial.Scientific reports · 2013Article
- Walking and running economy: inverse association with peak oxygen uptake.Medicine and science in sports and exercise · 2010Article
- Urine melatonin and citrate excretion during the elite swimmers' training season.European journal of applied physiology · 2010Article
- A high-throughput respirometric assay for mitochondrial biogenesis and toxicity.Analytical biochemistry · 2010Article
- In vivo oxidative capacity varies with muscle and training status in young adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2009Article
- Endurance capacity, not body size, determines physical activity levels: role of skeletal muscle PEPCK.PloS one · 2009Article
- Does oxidative capacity affect energy cost? An in vivo MR investigation of skeletal muscle energetics.European journal of applied physiology · 2009Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
An inverse relationship has been shown between running and cycling exercise economy and maximum oxygen uptake (VO2max). The purposes were: 1) determine the relationship between walking economy and VO2max; and 2) determine the relationship between muscle metabolic economy and muscle oxidative capacity and fiber type. Subjects were 77 premenopausal normal weight women. Walking economy (1/VO2max) was measured at 3 mph and VO2max during graded treadmill test. Muscle oxidative phosphorylation rate (OxPhos), and muscle metabolic economy (force/ATP) were measured in calf muscle using 31P MRS during isometric plantar flexion at 70 and 100% of maximum force, (HI) and (MI) respectively. Muscle fiber type and citrate synthase activity were determined in the lateral gastrocnemius. Significant inverse relationships (r from -0.28 to -0.74) were observed between oxidative metabolism measures and exercise economy (walking and muscle). Type IIa fiber distribution was inversely related to all measures of exercise economy (r from -0.51 to -0.64) and citrate synthase activity was inversely related to muscle metabolic economy at MI (r = -0.56). In addition, Type IIa fiber distribution and citrate synthase activity were positively related to VO2max and muscle OxPhos at HI and MI (r from 0.49 to 0.70). Type I fiber distribution was not related to any measure of exercise economy or oxidative capacity. Our results support the concept that exercise economy and oxidative capacity are inversely related. We have demonstrated this inverse relationship in women both by indirect calorimetry during walking and in muscle tissue by 31P MRS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.