ReviewInternational journal of colorectal disease2006
The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence.
Review in International journal of colorectal disease, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- A systematic review and meta-analysis for the association of the insulin-like growth factor1 pathway genetic polymorphisms with colorectal cancer susceptibility.Frontiers in oncology · 2023Pooled it
- Consumption of red meat and processed meat and cancer incidence: a systematic review and meta-analysis of prospective studies.European journal of epidemiology · 2021Pooled it
- The Insulin-like Growth Factor System and Colorectal Cancer.Life (Basel, Switzerland) · 2022Review
- Colorectal Cancer in Younger Adults.Hematology/oncology clinics of North America · 2022Review
- Matrix Metalloproteinases in Chemoresistance: Regulatory Roles, Molecular Interactions, and Potential Inhibitors.Journal of oncology · 2022Review
- Sugar-sweetened beverage, artificially sweetened beverage and sugar intake and colorectal cancer survival.British journal of cancer · 2021Article
- Therapeutic Effects of Polyphenols on the Treatment of Colorectal Cancer by Regulating WntJournal of oncology · 2021Review
- Article
- Article
- Development of a Prediction Model for Colorectal Cancer among Patients with Type 2 Diabetes Mellitus Using a Deep Neural Network.Journal of clinical medicine · 2018Article
- SNPs in the Insulin-Like Growth Factor Gene and Obesity Impact on Colorectal Cancer in EgyptiansAsian Pacific journal of cancer prevention : APJCP · 2017Article
- MicroRNA-30a Inhibits Colorectal Cancer Metastasis Through Down-Regulation of Type I Insulin-Like Growth Factor Receptor.Digestive diseases and sciences · 2017Article
- Influence of dietary insulin scores on survival in colorectal cancer patients.British journal of cancer · 2017Article
- miR-448 suppresses proliferation and invasion by regulating IGF1R in colorectal cancer cells.American journal of translational research · 2016Article
- An exon variant in insulin receptor gene is associated with susceptibility to colorectal cancer in women.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer.PloS one · 2014Article
- The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells.Frontiers in endocrinology · 2014Review
- Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2010Article
- Article
- Postmenopausal estrogen and progestin effects on the serum proteome.Genome medicine · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this review is to clarify the involvement of the insulin-like growth factor (IGF) system in the development of colorectal malignancy. MATERIALS AND
methodsMedline searches were used to identify key articles relating the IGF system with the development of colorectal cancer.
resultsThe IGF system has been linked to colorectal malignancy by a convergence of data from epidemiological, clinical and laboratory-based sources.
conclusionFurther work is needed to characterise the IGF system expression in the colon. Such clarification could lead to the identification of targets that can be manipulated for clinical advantage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.