ArticleJournal of virology2005
Characterization of a novel vpu-harboring simian immunodeficiency virus from a Dent's Mona monkey (Cercopithecus mona denti).
Article in Journal of virology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 43 citations in OpenAlex.
- Simian Immunodeficiency Virus SIVgsn-99CM71 Vpu Employs Different Amino Acids To Antagonize Human and Greater Spot-Nosed Monkey BST-2.Journal of virology · 2022Article
- Conserved recombination patterns across coronavirus subgenera.Virus evolution · 2022Article
- Review
- Population Genomics Reveals Incipient Speciation, Introgression, and Adaptation in the African Mona Monkey (Cercopithecus mona).Molecular biology and evolution · 2021Article
- Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs.Journal of virology · 2020Article
- Discovery and full genome characterization of a new SIV lineage infecting red-tailed guenons (Cercopithecus ascanius schmidti) in Kibale National Park, Uganda.Retrovirology · 2014Article
- Adaptation to the interferon-induced antiviral state by human and simian immunodeficiency viruses.Journal of virology · 2013Article
- Macaque-tropic human immunodeficiency virus type 1: breaking out of the host restriction factors.Frontiers in microbiology · 2013Article
- New STLV-3 strains and a divergent SIVmus strain identified in non-human primate bushmeat in Gabon.Retrovirology · 2012Article
- Characterization of a monoclonal anti-capsid antibody that cross-reacts with three major primate lentivirus lineages.Virology · 2012Article
- Counteraction of tetherin antiviral activity by two closely related SIVs differing by the presence of a Vpu gene.PloS one · 2012Article
- Tetherin and its viral antagonists.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2011Review
- The presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 are not always linked in primate lentiviruses.Journal of virology · 2011Article
- Modulation of HIV-1-host interaction: role of the Vpu accessory protein.Retrovirology · 2010Review
- HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms.Molecular aspects of medicine · 2010Review
- BST-2/tetherin: a new component of the innate immune response to enveloped viruses.Trends in microbiology · 2010Review
- The Vpu protein: new concepts in virus release and CD4 down-modulation.Current HIV research · 2010Review
- Anti-tetherin activities in Vpu-expressing primate lentiviruses.Retrovirology · 2010Article
- Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.AIDS research and human retroviruses · 2009Review
- Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.Cell host & microbe · 2009Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the identification of a new simian immunodeficiency virus (SIV), designated SIVden, in a naturally infected Dent's Mona monkey (Cercopithecus mona denti), which was kept as pet in Kinshasa, capital of the Democratic Republic of Congo. SIVden is genetically distinct from the previously characterized primate lentiviruses. Analysis of the full-length genomic sequence revealed the presence of a vpu open reading frame. This gene is also found in the virus lineage of human immunodeficiency virus type 1 (HIV-1) and chimpanzee immunodeficiency virus (SIVcpz) and was recently described in viruses isolated from Cercopithecus nictitans, Cercopithecus mona, and Cercopithecus cephus. The SIVden vpu coding region is shorter than the HIV-1/SIVcpz and the SIVgsn, SIVmon, and SIVmus counterparts. Unlike Pan troglodytes schweinfurthii viruses (SIVcpzPts) and Cercopithecus monkey viruses (SIVgsn, SIVmon, and SIVmus), the SIVden Vpu contains the characteristic DSGXES motif which was shown to be involved in Vpu-mediated CD4 and IkappaBalpha proteolysis in HIV-1 infected cells. Although it harbors a vpu gene, SIVden is phylogenetically closer to SIVdeb isolated from De Brazza's monkeys (Cercopithecus neglectus), which lacks a vpu gene, than to Cercopithecus monkey viruses, which harbor a vpu sequence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.