Evidence map›Paper›PMID 15956574›Full record

ArticleJournal of virology2005

Seroprevalence and genomic divergence of circulating strains of feline immunodeficiency virus among Felidae and Hyaenidae species.

Jennifer L Troyer, Jill Pecon-Slattery, Melody E Roelke, Warren Johnson, Sue VandeWoude, Nuria Vazquez-Salat, Meredith Brown, Laurence Frank, Rosie Woodroffe, Christiaan Winterbach and 6 more

Abstract read
In one paragraph

Article in Journal of virology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 160 citations in OpenAlex.

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  5. Equal contributions of feline immunodeficiency virus and coinfections to morbidity in African lions.International journal for parasitology. Parasites and wildlife · 2021
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 3 countries.

Jennifer L TroyerLaboratory of Genomic Diversity, National Cancer Institute-Frederick, Maryland 21702-1201, USA.
Jill Pecon-Slattery
Melody E Roelke
Warren Johnson
Sue VandeWoude
Nuria Vazquez-Salat
Meredith Brown
Laurence Frank
Rosie Woodroffe
Christiaan Winterbach
Hanlie Winterbach
Graham Hemson
Mitch Bush
Kathleen A Alexander
Eloy Revilla
Stephen J O'Brien
Colorado State University · USFrederick National Laboratory for Cancer Research · USNational Cancer Institute · USScience Applications International Corporation (United States) · USConsejo Superior de Investigaciones Científicas · ESNational Zoological Park · USUniversity of California, Berkeley · USUniversity of California, Davis · USUniversity of Oxford · GB

Funding

The Genetic Structure of Natural Populations Past and PresentZ01BC005367 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI O'BRIEN, STEPHEN J · 1996 to 2008
$2.0M
NCI NIH HHS N01 CO012400NCI NIH HHS N01-CO-12400
6 · The paper itself

Abstract

Feline immunodeficiency virus (FIV) infects numerous wild and domestic feline species and is closely related to human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). Species-specific strains of FIV have been described for domestic cat (Felis catus), puma (Puma concolor), lion (Panthera leo), leopard (Panthera pardus), and Pallas' cat (Otocolobus manul). Here, we employ a three-antigen Western blot screening (domestic cat, puma, and lion FIV antigens) and PCR analysis to survey worldwide prevalence, distribution, and genomic differentiation of FIV based on 3,055 specimens from 35 Felidae and 3 Hyaenidae species. Although FIV infects a wide variety of host species, it is confirmed to be endemic in free-ranging populations of nine Felidae and one Hyaenidae species. These include the large African carnivores (lion, leopard, cheetah, and spotted hyena), where FIV is widely distributed in multiple populations; most of the South American felids (puma, jaguar, ocelot, margay, Geoffroy's cat, and tigrina), which maintain a lower FIV-positive level throughout their range; and two Asian species, the Pallas' cat, which has a species-specific strain of FIV, and the leopard cat, which has a domestic cat FIV strain in one population. Phylogenetic analysis of FIV proviral sequence demonstrates that most species for which FIV is endemic harbor monophyletic, genetically distinct species-specific FIV strains, suggesting that FIV transfer between cat species has occurred in the past but is quite infrequent today.

Indexed as

Genetic VariationAmino Acid SequenceAnimalsAntigens, ViralBase SequenceCarnivoraCatsDNA PrimersFelidaeGenome, ViralHyaenidaeImmunodeficiency Virus, FelineMolecular Sequence DataPhylogenyPolymerase Chain ReactionAntigens, ViralDNA Primers

Identifiers

PMID15956574
PMCPMC1143723
OpenAlexW2118066208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.