Evidence map›Paper›PMID 15956560›Full record

ArticleJournal of virology2005

Promoters, transcripts, and regulatory proteins of Mungbean yellow mosaic geminivirus.

P V Shivaprasad, Rashid Akbergenov, Daniela Trinks, R Rajeswaran, K Veluthambi, Thomas Hohn, Mikhail M Pooggin

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 135 citations in OpenAlex.

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  19. Differential responses ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2020
    Article
  20. Geminivirus Resistance: A Minireview.Frontiers in plant science · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

P V ShivaprasadInstitute of Botany, University of Basel, Schönbeinstrasse 6, CH-4056 Basel, Switzerland.
Rashid Akbergenov
Daniela Trinks
R Rajeswaran
K Veluthambi
Thomas Hohn
Mikhail M Pooggin
Madurai Kamaraj University · INUniversity of Basel · CHFriedrich Miescher Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Geminiviruses package circular single-stranded DNA and replicate in the nucleus via a double-stranded intermediate. This intermediate also serves as a template for bidirectional transcription by polymerase II. Here, we map promoters and transcripts and characterize regulatory proteins of Mungbean yellow mosaic virus-Vigna (MYMV), a bipartite geminivirus in the genus Begomovirus. The following new features, which might also apply to other begomoviruses, were revealed in MYMV. The leftward and rightward promoters on DNA-B share the transcription activator AC2-responsive region, which does not overlap the common region that is nearly identical in the two DNA components. The transcription unit for BC1 (movement protein) includes a conserved, leader-based intron. Besides negative-feedback regulation of its own leftward promoter on DNA-A, the replication protein AC1, in cooperation with AC2, synergistically transactivates the rightward promoter, which drives a dicistronic transcription unit for the coat protein AV1. AC2 and the replication enhancer AC3 are expressed from one dicistronic transcript driven by a strong promoter mapped within the upstream AC1 gene. Early and constitutive expression of AC2 is consistent with its essential dual function as an activator of viral transcription and a suppressor of silencing.

Indexed as

Promoter Regions, GeneticTranscription, GeneticBase SequenceCloning, MolecularDNA, CircularDNA PrimersDNA, Single-StrandedDNA, ViralGeminiviridaeGenome, ViralMolecular Sequence DataPhaseolusReverse Transcriptase Polymerase Chain ReactionViral ProteinsDNA, CircularDNA PrimersDNA, Single-StrandedDNA, ViralViral Proteins

Identifiers

PMID15956560
PMCPMC1143740
OpenAlexW2049090999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.