ArticleArchives of disease in childhood2006
The re-emerging burden of rickets: a decade of experience from Sydney.
Article in Archives of disease in childhood, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Serum 25-hydroxyvitamin D threshold and risk of rickets in young children: a systematic review and individual participant data meta-analysis to inform the development of dietary requirements for vitamin D.European journal of nutrition · 2024Pooled it
- Vitamin D as an adjunct to antibiotics for the treatment of acute childhood pneumonia.The Cochrane database of systematic reviews · 2023Pooled it
- Vitamin D as an adjunct to antibiotics for the treatment of acute childhood pneumonia.The Cochrane database of systematic reviews · 2018Pooled it
- Trial
- The impact of rickets on growth and morbidity during recovery among children with complicated severe acute malnutrition in Kenya: A cohort study.Maternal & child nutrition · 2018Trial
- Trial
- Study protocol--metabolic syndrome, vitamin D and bone status in South Asian women living in Auckland, New Zealand: a randomised, placebo-controlled, double-blind vitamin D intervention.BMC public health · 2008Trial
- Early life nutrition in Nunavut, Canada: a retrospective descriptive study of food security, vitamin D and rickets.International journal of circumpolar health · 2025Article
- Oral Versus Injectable Vitamin D Therapy for Treating Nutritional Rickets in Indian Children: A Comparative Study.Indian journal of orthopaedics · 2025Article
- Physiology of Vitamin D-Focusing on Disease Prevention.Nutrients · 2024Review
- Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement.The Journal of clinical endocrinology and metabolism · 2023Article
- Main nutritional deficiencies.Journal of preventive medicine and hygiene · 2022Review
- Vitamin D, rickets and child abuse: controversies and evidence.Pediatric radiology · 2021Review
- Nutritional rickets & osteomalacia: A practical approach to management.The Indian journal of medical research · 2020Review
- Screening of vitamin D and calcium concentrations in neonates of mothers at high risk of vitamin D deficiency.BMC pediatrics · 2020Article
- An Overview of Rickets in Children.Kidney international reports · 2020Review
- Micronutrient deficiencies and health-related quality of life: the case of children with vitamin D deficiency.Public health nutrition · 2020Article
- The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery.Journal of orthopaedic surgery and research · 2020Article
- Vitamin D, and Maternal and Child Health.Calcified tissue international · 2020Review
- Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo define the demographics and clinical characteristics of cases presenting with nutritional rickets to paediatric centres in Sydney, Australia.
methodsRetrospective descriptive study of 126 cases seen from 1993 to 2003 with a diagnosis of vitamin D deficiency and/or confirmed rickets defined by long bone x ray changes.
resultsA steady increase was seen in the number of cases per year, with a doubling of cases from 2002 to 2003. Median age of presentation was 15.1 months, with 25% presenting at less than 6 months of age. The most common presenting features were hypocalcaemic seizures (33%) and bowed legs (22%). Males presented at a younger age, with a lower weight SDS, and more often with seizures. The caseload was almost exclusively from recently immigrated children or first generation offspring of immigrant parents, with the region of origin predominantly the Indian subcontinent (37%), Africa (33%), and the Middle East (11%). Seventy nine per cent of the cases were born in Australia. Eleven cases (all aged <7 months) presented atypically with hyperphosphataemia.
conclusionsThis large case series shows that a significant and increasing caseload of vitamin D deficiency remains, even in a developed country with high sunlight hours. Cases mirror recent immigration trends. Since birth or residence in Australia does not appear to be protective, screening of at risk immigrant families should be implemented through public health policies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.