ArticlePlant molecular biology2005
Arabidopsis Rad51B is important for double-strand DNA breaks repair in somatic cells.
Article in Plant molecular biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 53 citations in OpenAlex.
- Enhancing HR Frequency for Precise Genome Editing in Plants.Frontiers in plant science · 2022Article
- Deep Sequencing Discovery and Profiling of Known and Novel miRNAs Produced in Response to DNA Damage in Rice.International journal of molecular sciences · 2021Article
- RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis.PLoS genetics · 2021Article
- The rDNA Loci-Intersections of Replication, Transcription, and Repair Pathways.International journal of molecular sciences · 2021Review
- Structural Aspects of DNA Repair and Recombination in Crop Improvement.Frontiers in genetics · 2020Review
- DNA- and DNA-Protein-Crosslink Repair in Plants.International journal of molecular sciences · 2019Review
- The role of epicuticular waxes on foliar metal transfer and phytotoxicity in edible vegetables: case of Brassica oleracea species exposed to manufactured particles.Environmental science and pollution research international · 2019Article
- DNA Repair GeneInternational journal of molecular sciences · 2019Article
- The retinoblastoma homolog RBR1 mediates localization of the repair protein RAD51 to DNA lesions inThe EMBO journal · 2017Article
- The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis.The EMBO journal · 2016Article
- Homology-dependent repair is involved in 45S rDNA loss in plant CAF-1 mutants.The Plant journal : for cell and molecular biology · 2015Article
- DNA damage and repair in plants - from models to crops.Frontiers in plant science · 2015Review
- RAD51B plays an essential role during somatic and meiotic recombination in Physcomitrella.Nucleic acids research · 2014Article
- On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis.Frontiers in plant science · 2014Review
- Roles of XRCC2, RAD51B and RAD51D in RAD51-independent SSA recombination.PLoS genetics · 2013Article
- The rice RAD51C gene is required for the meiosis of both female and male gametocytes and the DNA repair of somatic cells.Journal of experimental botany · 2012Article
- Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation.Molecular microbiology · 2011Article
- Plant DNA recombinases: a long way to go.Journal of nucleic acids · 2010Article
- Recombination activator function of the novel RAD51- and RAD51B-binding protein, human EVL.The Journal of biological chemistry · 2009Article
- Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants.Journal of experimental botany · 2009Article
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rad51 paralogs belong to the Rad52 epistasis group of proteins and are involved in homologous recombination (HR), especially the assembly and stabilization of Rad51, which is a homolog of RecA in eukaryotes. We previously cloned and characterized two RAD51 paralogous genes in Arabidopsis, named AtRAD51C and AtXRCC3, which are considered the counterparts of human RAD51C and XRCC3, respectively. Here we describe the identification of RAD51B homologue in Arabidopsis, AtRAD51B. We found a higher expression of AtRAD51B in flower buds and roots. Expression of AtRAD51B was induced by genotoxic stresses such as ionizing irradiation and treatment with a cross-linking reagent, cisplatin. Yeast two-hybrid analysis showed that AtRad51B interacted with AtRad51C. We also found and characterized T-DNA insertion mutant lines. The mutant lines were devoid of AtRAD51B expression, viable and fertile. The mutants were moderately sensitive to gamma-ray and hypersensitive to cisplatin. Our results suggest that AtRAD51B gene product is involved in the repair of double-strand DNA breaks (DSBs) via HR.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.