Evidence map›Paper›PMID 15946586›Full record

ReviewCurrent oncology reports2005

The cancer anorexia/weight loss syndrome: therapeutic challenges.

Karin F Giordano, Aminah Jatoi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Cell-death induced immune response and coagulopathy promote cachexia inbioRxiv : the preprint server for biology · 2025
    Article
  3. The Power of Drosophila in Modeling Cancer Cachexia.Advances in experimental medicine and biology · 2025
    Review
  4. Article
  5. Cancer cachexia: lessons from Drosophila.Disease models & mechanisms · 2022
    Review
  6. Article
  7. Article
  8. Evolving classification systems for cancer cachexia: ready for clinical practice?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2010
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karin F GiordanoDepartment of Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Aminah Jatoi
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cancer anorexia/weight loss syndrome is characterized by loss of weight, loss of appetite, overall decline in quality of life, and shortened survival in patients with advanced incurable cancer. It is highly prevalent. To date, treatment options that have been firmly established with good scientific evidence are limited to progestational agents and corticosteroids, both of which have been demonstrated to improve appetite but have otherwise failed to have a favorable impact on some of the other aspects of this syndrome. As the mechanisms behind this syndrome are further elucidated, more effective therapeutic strategies will likely emerge.

Indexed as

AnorexiaClinical Trials as TopicHumansNeoplasmsProteasome Endopeptidase ComplexSignal TransductionSyndromeTumor Necrosis Factor-alphaUbiquitinWeight LossProteasome Endopeptidase ComplexTumor Necrosis Factor-alphaUbiquitin

Identifiers

PMID15946586
OpenAlexW1981978731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.